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To What Extent are Humans Optimized?

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What do you mean, human brains "might" use analog computation? I wasn't aware human brains did any digital computation.

? The conventional view is that human brains are digital computers. Information is represented symbolically in the form of nerve impulses, which is what enables the otherwise uniform computational substrate of the cerebrum to otherwise be able to process such a variety of different things from simple sensation to the considerations involved in complex planning etc.

Not of anyone aware of the fact that a single neuron can have thousands of dendritic spines that undergo constant remodeling.

Neurons are capable of responding to both frequency and amplitude of nerve impulses they receive

This just means that neurons don't work in binary like most artificial electrical computers, it doesn't mean they aren't components of a digital computer. Digital doesn't mean binary.

underlying biology is 100% analog.

From your comment I'm afraid you might just have no idea what a digital computer actually is. Whether information is transferred electrically or not isn't what separates digital computers from analog ones, but rather the fact that information is represented symbolically in digital computers and not in analog ones. Information is represented symbolically in the form of action potentials in neurons in the brain meaning it is a digital computer.

"otherwise uniform computational substrate of the cerebrum to otherwise be able to process such a variety of different things from simple sensation to the considerations involved in complex planning etc." is gobbledygook that explains nothing as far as neuroscience is concerned.

When you want to be a dick, you should at least try and know something of what you're talking about so you don't come across as both needlessly overconfident and a dick. The fact that neurons can process both sense information as well as consider things like complex planning means that by definition they must be the components of a digital computer. What is uniform about the substrate is that it is all composed of neurons, not whether the architecture happens to be similar or not across various cortical layers (just as the architecture of different computer processors is not uniform despite all being made of transistors.)