SerialStateLineXer
No bio...
User ID: 1345
SerialStateLineXer
1yr ago
If your browser has an unpatched, exploitable vulnerability, the sky's the limit. It shouldn't be possible for a web site to run malicious code on a simple page load, but browsers don't always work the way they should.
SerialStateLineXer
1yr ago
Assuming he means something like free, accurate AI tagging/filtering, how does that remove the incentive to call [objectionable thing X] worthy of proper censorship?
That's removing the conflation between moderation and censorship. It takes away the excuse that it's necessary for a good user experience because users don't want to see the content, and forcing censorship advocates to admit that they don't think that users should be allowed to see it.
SerialStateLineXer
1yr ago
It sure was lucky for the left that the Kochs aren't Jewish.
SerialStateLineXer
1yr ago
It's looking more and more like genetic engineering is the only viable way to close racial SES gaps. Ironically, the NIH is fighting to preserve racial inequalities while proclaiming its intent to narrow them.
SerialStateLineXer
1yr ago
If I ask you what’s the result of 22+2, you are most likely going to answer 24, but if I ask you what’s 22:00+2:00, you are likely not going to answer 24:00 (which isn’t a thing)
It's quite common in Japan to see a bar or restaurant with posted hours of operation from 17:00 to 27:00 (i.e. from 5:00 PM to 3:00 AM). 27:00 is valid in the same sense that 27/24 or 400° is valid; we might call it an "improper time."
You also don't specify whether 22:00 is time of day or duration. If it's a duration, then 24:00 is clearly the correct answer.
SerialStateLineXer
1yr ago
In doing GWAS, it's normal to use extremely low p thresholds to correct for the problem of multiple comparisons, right? I understand why it's important to do this, but doesn't this lead to exclusion of many SNPs with real but small impact? Or by "saturated" do they mean that they have a sample large enough to render this concern negligible?
SerialStateLineXer
1yr ago
That looks like a bug. The use of backticks didn't prevent the tildes from creating a strikethrough effect.
SerialStateLineXer
1yr ago
Nara Burns is an anime character? I always assumed that your user name was a reference to a historical event involving the burning of Nara, or maybe the annual festival where they burn text into the hillside in Nara.
SerialStateLineXer
1yr ago
What I would do myself: I'd go "yeah I knew it, wireless earbuds are a stupid product" and go back to wired forever.
I use wired headphones with a USB dongle on my Pixel 6. There's a loud white noise effect that plays whenever the volume falls below a certain threshold.
SerialStateLineXer
1yr ago
Well, some people eat chicken sashimi.
Torisashi, it's called. People expect it to taste bad, but it actually tastes better than cooked chicken, IMO.
It's probably dangerous in the sense that you're more likely to get food poisoning by eating it raw than by eating it cooked, but the chances are still low in absolute terms, at least based on my experience of eating raw chicken several dozen times and never getting sick.
SerialStateLineXer
1yr ago
A fat teenage boy tried to sell me a blowjob, and then just grabbed my crotch when he realized that telling me that he gave straight men blowjobs all the time wasn't working. I smacked his hand away and he left me alone. Like you, this freaked me out more than I would have expected it to, but only for the rest of the day or so. I didn't really do anything special to take my mind off it.
SerialStateLineXer
1yr ago
This comment awakened ancient memories within me, and I reflexively looked around for a link to a site selling counterfeit handbags or something.
SerialStateLineXer
1yr ago
On the other side of the spectrum, of course, you have the shit-test case, where you rally behind the most unsympathetic, obviously in-the-wrong person you can find and dare people to call you on it.
SerialStateLineXer
1yr ago
In Merck's recent press release for the results of their phase 2 melanoma trial, they said this:
Adjuvant treatment with mRNA-4157/V940 in combination with KEYTRUDA reduced the risk of recurrence or death by 44% (HR=0.56 [95% CI, 0.31-1.08]; one-sided p value=0.0266) compared with KEYTRUDA alone.
Does that confidence interval look wrong to anyone else? It should be geometrically symmetrical around the point estimate, right?
-
0.56/0.31 = 1.81
-
1.08/0.56 = 1.93
Even making the most accommodating assumptions about rounding, I can't make the math work out:
0.5649 / 0.3050 * 0.5649 = 1.046
Also, 1.08 is weirdly far from 1 given that the one-tailed p value is only 0.0266. I would expect it to be just barely greater than 1.
SerialStateLineXer
1yr ago
It's not a question of how wide the confidence interval is, but of how much of the interval is greater than 1. For a 95% confidence interval, a one-tailed p of 0.025 should correspond to a CI with an upper (or lower) bound of 1.0. Since the p value is only slightly greater than 0.025, I would expect the upper bound of the CI to be closer to 1.
I checked confidence intervals of hazard ratios for several other published studies and found that the CIs were consistently geometrically symmetrical (i.e. upper/point = point/lower) around the point estimate, but now that I think about it, they all had large samples. I'll have to look into why small sample can result in asymmetric confidence intervals.
SerialStateLineXer
1yr ago
The strongest justification for a large award is to recover the ill-gotten gains of Jones.
The state in which the lawsuit occurred explicitly does not allow punitive damages (I can't remember how general this rule is, but it applied to Jones' case), which is why the compensatory damages were so high. As I said at the time, using inflated compensatory damages to circumvent a ban on punitive damages certainly seems legally dubious to me, with the caveat that I'm not a lawyer.
This is not my area of expertise, but I'd expect that to lead to much larger distances on the right tail.
It does, but I accounted for that. The right tail is longer than expected even when accounting for the fact that it's logistic. Either there's something I'm not understanding about how this works, or someone screwed up somewhere.
SerialStateLineXer
1yr ago
I looked it up again, and the issue was that in Connecticut, juries cannot award punitive damages, but judges can. In Texas, there's a cap on punitive damages which the judge ignored, so that will likely be challenged.
SerialStateLineXer
1yr ago
In practice, true underrepresentation-as-tiebreaker practices are just not that big a deal for over- or proportionally represented candidates. The reason certain groups are underrepresented in certain positions is that they're underrepresented among qualified applicants, often dramatically. There just aren't that many to compete with, relative to the slots to be filled.
I guess one exception might be US Asians competing against whites, because we outnumber them so much. Tech companies aren't using race as a tiebreaker between Asians and whites, but universities probably are.
The bigger issue, as you say, is the bailey, where "tie" is defined loosely enough for a half-sigma difference to count as a tie.
SerialStateLineXer
1yr ago
Some Supreme Court justices are better than others in some abstract sense, but in practice, the main consideration is that the appointee should reliably take the appointing party's side while being creative and erudite enough to avoid looking like too much of a hack while doing it.
The white homicide rate in the US is somewhere around 2.5-3 per 100K
In 2019, the homicide victimization rate for non-Hispanic whites was 2.6. With accounting for asymmetric interracial homicide, the rate of offending was probably under 2.5 per 100k.
Source: CDC, Deaths: Final Data for 2019, table 9. 2020 data should be out by now, but I haven't been able to find it.
Edit: According to the first reference here, Deaths: Final Data for 2020 is still "forthcoming" as of this month. I guess they're busy with COVID stuff?
SerialStateLineXer
1yr ago
That's a summary report. The full report is like a hundred pages with statistics for over a hundred different causes of death broken down by multiple demographic stats. Here's the report for 2019:
SerialStateLineXer
1yr ago
Specifically, IQ is positively correlated with classical liberalism. As a classical liberal, this doesn't bother me much.
SerialStateLineXer
1yr ago
I was going to post my analysis, but this guy already did a much more in-depth analysis than I have the patience for:
https://cremieux.substack.com/p/black-economic-progress-after-slavery
TL;DR: As noted in the abstract of the paper itself, the gap appears to be driven almost entirely by state of residence, with southern but not northern blacks having been exposed to Jim Crow (the main analysis is in 1940, and the extended analysis only goes through 2000). There's also likely some selection bias, with more productive slaves being more likely to be freed.
In short, this provides basically zero evidence for the effects of truly exogenous poverty persisting for more than a generation or two once the impoverishing forces are removed.
Cavity remineralization is a well-documented phenomenon, though fluoride assists in this process, rather than inhibiting it. Note that it's a fairly limited process; if you have substantial enamel loss, you can't rebuild it through remineralization.
Excessive fluoride intake can result in skeletal fluorosis, which can be severely debilitating in extreme cases, but it requires levels far in excess of those found in fluoridated water. The evidence that it prevents tooth decay is fairly strong, but if you're doing everything else right, you don't really need it.
The other advice is mostly okay, if excessive. The main things I would recommend are limiting refined carbohydrates and acidic drinks, brushing and flossing, and getting enough vitamin D and K2. Sugar is particularly bad; you know that sour taste you get in your mouth when you eat too much sugar? That's the acid produced by oral bacteria metabolizing the sugar.
More options
Context Copy link