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disposablehead

Hipster eugenicist

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joined 2022 September 05 03:50:16 UTC
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User ID: 426

disposablehead

Hipster eugenicist

0 followers   follows 0 users   joined 2022 September 05 03:50:16 UTC

					

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User ID: 426

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There is the implication here that Ukrainians have, or should have, a kinship with Russia (similar to the kinship between Sweden and Finland), and I simply do not think this follows. I, in fact, have been under the impression that Ukrainians already didn't like Russia long before the events of the Euromaidan, as they very much wanted nothing to do with the legacy of Communism and the USSR.

Definitely not what I meant. Think more in terms of Hong Kong and China, or the varied demands America has placed on Central and South American states vis a vis drug manufacturing; some shared history, but most of it is a big player who gets to tell small players what to do. But since there isn’t any doubt that the big kids wins every fight, we don’t have entire cities reduced to rubble.

I think you’ve also papered over the real ethnic differences that underlie the ongoing conflicts in the Donbas for the past 10 years, although you certainly aren’t alone there. Western Catholic Ukrainians want to join the west and Eastern Orthodox Ukrainians want to reintegrate with Russia. This conflict wouldn’t have happened if splinter states for ethnic Russians were permitted, as the local referenda asked for. This war is not a noble fight between a tyrant and an underdog, but a civil war backed by opposing global powers. Seems bad to me.

Does the invasion even happen without the CIA providing intelligence and training for the Ukrainians? Is Minsk II ignored without American armaments and implicit support? Yarvin says we don’t have this war without western deep state meddling, and that seems trivially true. Ukraine as Russian client state saves a lot of lives. If it’s worth it is a separate question, for Americans, Ukrainians, and Poles.

After digging out 3 boxes of tattered 2001 era MtG cards from my childhood closet, I want to get back into the game but I’m not sure where to start. I have a handful of nice cards that have aged well; a vampiric tutor, some common-rarity Rhystic Study’s, some old shocklands, but everything else looks severely power-creeped. Should I start going to drafts? Just grab a prefab commander deck? Smash random shit together and just show up?

Do you feel like regular use of Tylenol is wrong?

I suspect that people transpose a dislike for the medical system onto the things the system controls. If you had to cajole an ethanol prescription from your PCP every 3 months your relationship to booze would seem craven and desperate, even holding the quantity and quality constant. If you could pick up amphetamines at your local gas station, would it still feel so gross?

Biologics are a big category, of which the -mabs are the early success story. The next evolution would be exactly what you described, where we can construct a protein to block targets by way of a fancy ml chemistry algorithm instead of trial and error. Beyond that, we get into de novo synthetic proteins that have more in common with sci-fi nanomachines than penicillin. Then, ???.

The Jumpstart 2020 and 2022 sets are great for beginners. Each booster pack has cards from a single color and theme, and you can shuffle 2 packs together to make something that plays out like strong limited or draft decks. You can get a booster box of 24 packs for ~$100 and treat it like a cube. Highly recommend.

Card Kingdom sometimes puts out ‘Battle decks’, which are a cheap way to get playable 60 card decks that feel strong enough. Nothing too crazy, but good for kitchen table games.

Draft or limited are super fun but very very challenging and not for beginners.

Commander can actually be fun but it very much depends on the play group. If all 4 players are chill and playing decks of similar power then the format can be fun, but it’s often pretty complex and politics plays a big role. It’s definitely the most popular format and the easiest to find IRL games for, and it isn’t too hard to build a budget deck for $50-100 that plays perfectly well in low power pods. All that said, the format allows huge variation, and the experience of playing against a high-powered deck with a budget deck can be torture. If your kid wants to play with others this is eventually where you’ll probably end up but I wouldn't rush there.

It’s a pretty good prior tho, no? With an N= all British people 1600-2020 you could rank order each person per generation by Clarks’ variables, derive a temporal weight for each, then see who is at the top and bottom, and the rank of their relatives. As is, Clark has to do a lot of estimations, tho he does try to justify them. The alternative hypothesis would have to find a reservoir for status outside of money, occupation, or education, which seems plausible but I’m personally drawing a blank for possibilities.

Not necessarily, because house value is a proxy for social status that depends on its contextual weight. If London is burnt to the ground, or becomes much more expensive, the relationship between social status and house value changes, but the underlying heritability of social status remains the same. If everyone had cheap houses, it doesn’t mean that the society has more social mobility, just that that variable doesn’t capture status any more. Note figure 3, where wealth has much weaker maternal heritability compared to occupational status and education.

My bad, posted off the cuff and should have been more granular and done a bit more research. The conflict best maps as Catholics + Ukrainian Orthodox vs Russian Orthodox. This link from 2021 has UOC-MP as the largest denomination in the country, which is now 4% according to Wikipedia. Here’s a very nice map of the Ethnic/linguistic composition of Ukraine, notably missing from the exhaustive wiki page on Ukrainian demographics. I’m sure there’s more interesting West vs. East stuff I could dig up, but it’s not worth my time. We’re pwned, and it’s only going to get worse.

(Huh. This is what it must have felt like to be a Quaker during WWII.)

What of the democratic election of Yanukovych, based on support from the Eastern Russian speakers? What of the Donbas referendums for independence? The context for Ukrainian secession is more Bosnian War than Scottish progressives. This is Eastern Europe, my man; the legends aren’t good, but Грозный.

There’s a big difference between technical capacity and legal or economic feasibility. We’re already past replacing bad docs with LLMs; you could have a nurse just type up symptoms and do the tests the machine asks for. But legally this is impossible, so it won’t happen. We can’t hold a machine responsible, so we need human managers to insure the output is up to standards; but we don’t need lawyers to write contracts or programmers to code, just to confirm the quality of output. It isn’t as clever as the smartest scientists yet, but that seems easily solvable with more compute.

HBD is a useful scientific frame insofar as it goes against the default blank-statist universalism of academia writ large, but the number of people who truly give a shit about the phenotypic variance populations on psychometrics is a rounding error. The issue is that people like to make interventions which don’t do anything. We can quibble over effect sizes, but right now I could use embryo selection to get a marginally smarter child compared to controls. There isn’t any known environmental intervention that can more the dial on adult g.

I’m actually quite sympathetic to giving more credit to random noise, but nobody has time for the humility that would demand.

Roller mobster goes way too hard

What are y’all listening to?

I just discovered Lunar Society and I was blown away. The guest list is great but I’m most impressed by Dwarkesh’s ability to think through a statement and find something to push back. Very highly recommended.

The above passage is IMO a very clever way of framing Jews and Jewish racial traits as foundational to not only sexual liberalism and communist worldviews but to those of the trad-cons and the alt-right itself. It’s as pro-Semitic as a race-realist speaking to an audience of Hitlerite memers could probably get without getting cancelled.

The offensiveness arguably serves to stop the process of dilution and appropriation as depicted in Geeks, MOPs, and sociopaths. You can’t take the homophobic slurs into the mainstream, so arguably you get to keep your ghetto free of grifters and maintain the spirit of contrarianism necessary for original thought.

Does Nietzsche have any specific policy platform? This is a distinct culture separate from neoliberal wonkery and it doesn’t express itself in that language, in the same way utils don’t make sense outside of a consequentialist framework. Their political goal is a new regime, with the specifics TBD, because their framework boils down to good leaders with real power -> good country. Again, naive IMO, but I appreciate that they are trying to build something.

There’s a subtle variant of racism 0HP advocates for that I’m coming to agree with but doubt I can communicate clearly. Too much of an inferential gap. I can give it a shot if you’re curious, but if you don’t agree with basic race-realist stuff it probably won’t get us anywhere.

It’s easier to find a good critique than a good solution, and to his credit, 0HP has at least one pointed in the vague direction of a real solution in the form of his Christo-Nietzchean synthesis. The Neo-Nietzchean fake-and-gay critiques I suspect are correct, though the crassness is not quite my cup of tea. My most substantial disagreement is with his hope in high-drama politics to guide reform; I think the next election cycle or three is doomed, and the more technocratic arguments of Hanania will have to win out.

Ban no-fault divorce, and add a huge increase to the tax benefits of both marriage and parenthood. In effect, a tax on being single, childless, or old.

He’s a modern version of Andy Kaufman. The rules have changed since the 60’s so Hyde’s transgressions are more provocative, but it’s basically the same act.

Antibodies are proteins your body makes to fight bad stuff. These are custom-made to stick to a specific target and tell your immune system what to attack, but sometime the target is a dumb mistake, like pollen, and you get allergies, or the target is correctly chosen but it looks just like some other innocent molecule, and you get autoimmunity. There are other systems to dial back unnecessary immune activity, but these have less evolutionary weight than pathogen defense so they’re a bit wimpy.

You can increase the risk of developing an allergy by regularly exposing someone to a scary-looking molecule and have some chance of making them develop an allergy, i.e. regular exposure to latex can lead to a banana allergy. But antibodies are generated in a pseudorandom manner, so you can’t guarantee a bad reaction, just roll a few more dice.

It’s more like: we should expect for life to colonize as much of the universe as it can. Since we can’t see other life in our lightcone, we are probably in the early days of universe colonization. A secondary claim would be: you should expect to be born into the most populous point in history. You are born now, so the very plausible interstellar future is somehow less populated than today. A very plausible mechanism is selection towards a singular group or individual that does all of the future colonization.

I don’t know, 1 train line to nowhere seems more cost effective than 0, especially when people can build around the new infrastructure.

Sounds like a market opportunity to me. Why aren’t there Bond-villain type organizations that kill for profit alone? Was RICO that effective?

So, to put it in some context: the criticism of GWAS has always been that these studies are large, expensive, rarely teach us anything about the underlying biology and explain little of the actual heritability (‘missing heritability’ problem). The ‘mechanistic’ biologists interested in curing disease or engineering biology generally dislike GWAS.

The development of big GWAS and tools like AlphaFold suggest to me that we’re nearing the point where useful empirical information overwhelms the capacities of human comprehension. The etiology of Alzheimer’s might just be Ala->Gly x100, and the true story is an overwhelming mass of minutiae, compared to the comprehensible ‘protein x is broken’. A lot of the work of medicine has been outsourced to evolution, and we’ve cribbed from her notes on every antibiotic and biologic we’ve produced. But we’re getting close to the point where we can build magic bullets from first principles.

I’ve been thinking about an inverse failure mode in medicine, where snake oil is ruthlessly exterminated but good medicine is expensive, hard to get, and slow to get to market. A fool and his money are easily parted, so we still have plenty of hookum sold to the gullible, but they aren’t taking real drugs with serious side effects, or so the argument goes.

Medicine would be better for some substantial % of the populous if they could just take whatever drugs they wanted. Others would very rapidly harm themselves. A two-tiered system where people can take whatever they want after jumping through hoops seems superior to either extreme, but we already kind of have that, where patients bug their PCP until they get the drugs they want. But we still have exploitation through med advertisements, Medicare fraud, etc., and we lack the freedom to import specialized baby formula or try even mildly novel compounds.

I like free speech maximalism in social media on the grounds that there isn’t a 1:1 tradeoff between freedom and truth. Less freedom often means less truth, as lying is a powerful tool if you can get away with it. Can you shut down the scammers at all without breaking some other load-bearing norm? It might be the case that social media is net negative, but the milk is spilt in that regard. Why not other regulatory angles tho? Finance is tightly regulated so changing the rules about investment products seems safer than throwing out an key amendment.

The Culture should definitely be on your list. Player of Games and Excession are total bops