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Notes -
Sadly, I must refer you back to the "it hasn't been properly studied" point above. "No conclusions can be drawn" is basically a constant refrain in the Cass Review.
I think the first time I heard about it was with the case of Jazz Jennings, the rest is connecting the dots from what gender clinicians say themselves. From another post of mine:
One note: I did adjust my position somewhat since writing it. Recently I've seen an interview with a guy that had hypogonadism, basically the opposite of precocious puberty, where his body didn't want to trigger normal development. Apparently doctors managed to get him mostly up to speed where he now looks and acts (the lack of puberty also affected his psychology) like a normal bloke, so from this I figure it's not as bad as I thought. I keep promising myself I'll look into the literature on his condition, since if it describes what happens when it's untreated, that should give a non-politicized answer to the question of what happens due to puberty blockers, but I haven't found the time / motivation to do so yet.
I've also know of at least one detrans woman who managed to get pregnant post-testosterone (I think there are even non-detrans females that gave birth while constantly taking hormones). This is all in contrast to the blockers+hormones case, where I see gender clinicians themselves getting nervous, trying to adjust time-tables, and hacking around the issue, as per the quote above.
Sorry if it's conjecture, but I don't think anyone has actual data on this (or they do, but keep it secret, which wouldn't be surprising either at this point).
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