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Well I had covid twice so far while some people took over 3 injections.
Obviously a natural infection of a certain dose of particles through the nose or mouth is not the same as an injection in the arm in terms of dose, immune response, affected tissues...
And these triple-shot people are still getting sick!
Covid doesn't have it but a lot of viruses do.
What happens when somebody that was previously infected with a virus gets the injection?
Another factor to consider is that enzyme are only catalyzing chemical reactions.
Technically, these chemical reactions can occur spontaneously without enzymes as well.
If for whatever reason the RNA is getting concentrated in a given cell, perhaps a certain amount of them can end up spontaneously turning into DNA and getting captured by the cell machinery and getting integrated into the genome.
Another option is that the RNA gets cut into pieces and ends up having inhibitory effects on certain parts of the genome, upregulating or downregulating proteins that are needed for a healthy body.
This could happen for some people and not others depending on their specific genome, or even depending on their microbiome.
There are so many possibilities on what can go wrong depending on the dose, depending on which cells might preferentially accumulate the RNA, depending on the specific genome of the injected, depending on infections from other viruses, depending on the strength of the immune system...
Again, this is for a virus that is more or less as harmful as the flu ie not very.
What I need, instead of 'fact-checking' by 'experts' with no physical, scientific evidence that for example 'RNA cannot integrate the genome', is studies.
Show me that after looking at the cellular, tissue level among hundreds or thousands of people that you could not find one cell producing spikes long after the injection. That you can't find one sample of tissue affected by long-term injection consequences.
Why do I have this standard?
Because the people demanding for 2 years that I take that unnecessary, cosmetic injection are the same that have been claiming that boys can turn into women by taking hormones and slicing themselves. The same people that claimed that Iraq had WMD. The same people that tell me that crime statistics are racist, etc, etc.
it is not at all obvious the latter is worse in some sense than the former. for one, the covid virus can replicate itself, while the mrna particles cannot
as has been stated hundreds of times, the vaccine clearly is not preventing transmission, probably for the same reason both 1.5^x and 8^x both increase with time. but it is effectively preventing death
... have you taken a high school biology class? "Technically, these chemical reactions can occur spontaneously without enzymes as well" ... not really, no. this is technically true if 'can occur spontaneously' has a rate of 10^-500/second or something.
As you note, normal viruses constantly integrate themselves into the genomes of your cells. It's an "intended" part of some of their lifecycles! And even if the mrna vaccine can do that, then ... so can covid. So why is the vaccine worse than covid?
It was significantly more harmful than the flu for older people, and everyone gets flu vaccines anyway
they also demand you wear seatbelts and not pour gasoline on the ground.
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Viruses replicate, in a way that the mRNA vaccine...doesn't? And goes into your bloodstream? And the receptor implicated in viral entry in COVID is expressed throughout the body.
Conversely, you get less systemic action (though still some) with the jab, because much of it stays pretty local to the injection site.
Most likely not very much, because:
Viral integrases are particular about what sequences they integrate, and...
A cell that is that actively translating viral reverse transcriptase is a cell that's...dying to the virus (if it wasn't being transcribed+translated and instead is in a provirus state, then there would be no issue), while a cell that is actively translating human reverse transcriptase is probably a cancer (or you're quite old, or it's differentiating, etc), and...
The mRNA vaccine might not even be readable, given that it isn't made with normal RNA nucleosides, and...
Even if it gets integrated it likely wouldn't do very much!
This is all talking about viral RTs; we humans have reverse transcriptase sequences in our genomes as well, from ancient retroviral infections (as you allude to). COVID itself possibly could be reverse transcribed into a small number of cell lines post-infection in a much less controlled manner, producing chimeric human-viral proteins. This would likely affect a small minority of people, and the actual health effects are pretty unclear.
Based on this, I would be much more worried about sequence integration post-infection compared to post-vaccine. At least you can engineer synthetic RNA-like molecules to be less recognisable by LINE1 retrotransposon RTs, and even if it happened, you can control the sequence being inserted.
It wouldn't just spontaneously turn into DNA. Reverse transcription is not a modification of the RNA sequence, it is a synthesis of new DNA strands based on the old one. Good luck doing that without an enzyme turning ATP into energy for that synthesis.
Have fun with that, biology is messy, and proving a negative is....well.
The spike protein could be produced if its sequence integrates into DNA.
What if there is so much RNA floating around that they just act in a more non-specific way?
Maybe. This is all about chemical logistics.
The assumption is that the mRNA is safe from integrating DNA because there is no reverse transcriptase packaged with it
turns out there could be cells containing reverse transcriptase but then the cells are probably dying so them getting spike DNA wouldn't matter
so we're assuming that the event won't happen because the enzyme and the RNA would not be together in the same cell
or that cell would not be producing spike protein for long
So it seems unlikely that we would have spike protein or some other type of foreign protein continuously produced after the injection. But then who knows what actually happens, until this is actually studied?
Did anybody test the same thing for injected people? That's what I'm asking for, before 'fact-checkers' assert that 'it's impossible'. Actually test it, then tell me whether it's possible or not. If one study finds no evidence of such a thing occurring in a large sample, it's better than a couple people hand-waving the issue away.
That seems correct. It seems that reverse transcriptase would be necessary for integration into DNA.
Not even making an attempt at providing evidence while simultaneously claiming something to be impossible is even worse. If it's impossible, at least produce evidence that you could not see it happen when you looked for it.
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