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naraburns  nihil supernum  1yr ago (text post)   31226 thread views

Culture War Roundup for the week of January 9, 2023

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CDC has released a report today finding preliminary association between the Pfizer vaccine and stroke for those over 65 years of age.

Another drop in the bucket - or is the bucket spilling out the top now?

https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/bivalent-boosters.html

Following the availability and use of the updated (bivalent) COVID-19 vaccines, CDC’s Vaccine Safety Datalink (VSD), a near real-time surveillance system, met the statistical criteria to prompt additional investigation into whether there was a safety concern for ischemic stroke in people ages 65 and older who received the Pfizer-BioNTech COVID-19 Vaccine, Bivalent.

Pfizer is associated significantly with strokes - CDC is keeping us in the dark about the exact data.

This preliminary signal has not been identified with the Moderna COVID-19 Vaccine, Bivalent. There also may be other confounding factors contributing to the signal identified in the VSD that merit further investigation. Furthermore, it is important to note that, to date, no other safety systems have shown a similar signal and multiple subsequent analyses have not validated this signal:

They then list multiple studies that did not replicate this finding for the BIVALENT vaccine - well of course, this vaccine was testing on mice, and then deployed without long term testing. Do they have monovalent data they are not mentioning?

EDIT: Is it possible monovalent risk benefit analysis is simply using a different pathogen, and now with the advent of Omicron, this is a medical update saying this level of strokes is no longer worth the benefit vs the current pathogen? Food for thought.

No change in vaccination practice is recommended.

This contradicts what Paul Offit's opinion is, which was posted in the NEJM. Paul Offit believes we should not give bivalent boosters to young healthy patients.

https://www.nejm.org/doi/full/10.1056/NEJMp2215780

It would be much more shocking to announce a chance to the vaccine campaign, than to keep the current inertia the same. I think we are seeing a communication strategy developing to deliver the population into accepting yearly mRNA vaccines - instead, they will be directed to other worthwhile candidates for vaccination - IF pharma companies can even deliver those.

In my eyes: mRNA vaccines are dangerous, so you need to determine how dangerous the pathogen presenting is. I see a great use case for mRNA developing for Airborne Ebola Zaire strains (90% mortality) or other disease of similar magnitude. Simply put: your vaccine should not significantly increase cardiovascular risk. It should be absolutely negligible. 1 in a million, whereas these vaccines might be 1 in 100,000.

You forgot this part:

When one system detects a signal, the other safety monitoring systems are checked to validate whether the signal represents an actual concern with the vaccine or if it can be determined to be of no clinical relevance.

and this part:

Although the totality of the data currently suggests that it is very unlikely that the signal in VSD represents a true clinical risk, we believe it is important to share this information with the public

which is probably why they said

No change in vaccination practice is recommended

Seems pretty reasonable.

And, you are being dishonest when you say:

They then list multiple studies that did not replicate this finding for the BIVALENT vaccine - well of course, this vaccine was testing on mice, and then deployed without long term testing.

The evidence they cite is:

● A large study of updated (bivalent) vaccines (from Pfizer-BioNTech and Moderna) using the Centers for Medicare and Medicaid Services database revealed no increased risk of ischemic stroke

● A preliminary study using the Veterans Affairs database did not indicate an increased risk of ischemic stroke following an updated (bivalent) vaccine

● The Vaccine Adverse Event Reporting System (VAERS) managed by CDC and FDA has not seen an increase in reporting of ischemic strokes following the updated (bivalent) vaccine

● Pfizer-BioNTech’s global safety database has not indicated a signal for ischemic stroke with the updated (bivalent) vaccine

Other countries have not observed an increased risk for ischemic stroke with updated (bivalent) vaccines

None of which seems to have anything to do with mice.

Yes, they say it's unlikely - but it's possible. SO now that we've established, it is unlikely, but possible that the vaccine can cause harm (which is occult and being undetected in other countries - if this possibility fleshes out).

No change in vaccination practice is recommended

The vaccination process will still be based heavily on a paradigm that humans MUST avoid circulating respiratory pathogens, yet if they must get infect, their best course of action is to take EUA vaccine (of which options are limited and you still cannot acquire an FDA approved and labelled vial of vaccine), at any age. They have said, the possibly the vaccine has a problem is not worth their time changing their public health campaign goal.

The evidence they cite is:

They do not submit any evidence regarding the monovalent vaccine. Yet the bivalent has the same synthetic mRNA transcripts as monovalent. Do we even know if bivalent mRNA is transcribed as a single strand, or seperated into two seperate mRNA molecules?

Not seeing any reason to get vaccinated for omicron, at almost any age or health, with an mRNA vaccine. We need a diversity of vaccines in this country, since efficacy is going to eventually drop for each mRNA boost.

SO now that we've established, it is unlikely, but possible that the vaccine can cause harm (which is occult and being undetected in other countries - if this possibility fleshes out).

No, from reading the report, they have a system which records symptoms in people who have received the vaccines and report side effects. There was a blip which they are required to investigate. The blip was "population at high risk of strokes are getting vaccinated and reporting strokes". So what has to be established is "does the vaccine cause, or elevate, a risk of having strokes?", and that was not established.

You could do a trial recording people who are in that age range (over 65) and do they report colds, sickness, arthritis flare-ups, gastro-intestinal problems and so forth after being administered a placebo, and see if that is reported. But we don't do that, because we expect people to have more health problems as they get older. Strokes and heart attacks are some of those problems. I'm sure that after getting the yearly flu vaccine, people also report first time strokes. But that doesn't mean the flu vaccine caused it, it means "you're over 65 and this is the risk of health problems you are going to have from now on".

Your own phrasing gives it away - hidden harm which is not detected in other countries, but you're sure it's happening anyway, because your prior is "The vaccine is dangerous" and you're grasping at straws to find anything to support that. So invisible danger nobody can find is there and that means the vaccines should be banned!

The vaccines are dangerous precisely because we are analyzing and looking for hidden harm, after we already administered a billion doses without fully understanding the consequences and outcomes.

mRNA cardiovascular toxicity is a severe problem and if it's at all likely, the hammer should drop. This "blip" is an 18 year old about to get mandated with mRNA bivalents before going to a community college.

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