The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:
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Requests for advice and / or encouragement. On basically any topic and for any scale of problem.
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Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.
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Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.
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Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).
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The whole point of the drug development pipeline is to minimize the unknown unknowns. Sure, it's not perfect, but there is no good reason to spend very much time worrying about Knightian uncertainty in a clinic. While your claims are true, I genuinely don't think it changes anything in practice. Statins have been around for ages, and even semaglutide has had its safety established to a degree where I am more than comfortable putting my mom on it and taking myself, sometimes.
And that's fine, no issues there. But when the pills are pretty close to a free lunch? I'm not advocating for him starting warfarin or anything that would make me sit up and think thrice before the recommendation.
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