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Wellness Wednesday for April 22, 2026

The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:

  • Requests for advice and / or encouragement. On basically any topic and for any scale of problem.

  • Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.

  • Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.

  • Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).

Jump in the discussion.

No email address required.

I've ticked off something that's been on the bucket list for a while: telling Gwern off for his nicotine essay, which hooked me, and many a stupid rat, on the chemical. It is a frankly terrible nootropic, even if the harms of "pure" nicotine (or even a vape) are minimal, the dependency is remarkably inconvenient and I'm quite confident that his advice is net negative EV. If I had a time machine, I'd give my past self a light smack on the head and told him to never start, alongside inside baseball knowledge on exam questions.

I would have said it to his face if I'd actually managed to meet him at Inkhaven, but hey, sneaking it into a wider debate about LLM prose is a victory nonetheless. I can sleep easier tonight.

Didn't you go for vaping, whereas Gwern specifically distinguished between gum/patches and vaping, even in the abstract of the essay?

Yes, but I still think Gwern underestimates how debilitating any nicotine dependency is.

He is absolutely correct that vaping or gum is a massive upgrade over an existing tobacco habit. But among the examples of alternatives that he considered "safe" for the nicotine-naive included snus, which was later found to increase all-cause mortality, particularly CV mortality. His speculation about the potential benefits wrt Alzheimer's or Parkinsons proved to be wrong on the basis of RCT evidence.

TLDR: It's a shit nootropic, the dependency risk is significant enough to be concerning even for gum or pouches. He didn't see the Zyn craze coming. His claims that medicinal NRT is remarkably non-addictive held up, but were clearly not applicable to recreational use. Switching away from smoking tobacco is massively positive, for someone who doesn't have a habit, don't start.

https://www.fda.gov/tobacco-products/health-effects-tobacco-use/relative-risks-tobacco-products#NewNic

While nicotine pouches can generally be a lower-risk alternative for adults who smoke cigarettes, the use of nicotine pouches is not risk free. Nicotine pouches contain nicotine, which is highly addictive, and can deliver harmful chemicals.

Given that there is no safe tobacco product, youth and adults who do not use tobacco products should not start using nicotine pouches.

You got nerd-sniped by ... nicotine? Keep us up to date on your efforts to kick the habit. We're rooting for you.

It's been almost 4 years, and I've found out, to my detriment, that quitting cold turkey is awful. During the periods where I am unavoidably separated from my vape, the best alternative I've found is nicotine gum, which keeps the worst of the withdrawal away. Otherwise? Brother, I'm fiending. I get angry and cranky, it's the closest I've gotten to PMSing, or what I'd imagine roid rage kinda feels like.

Quitting isn't a very high priority for me, right now. Mostly because the physical health risks of vaping are minimal, close to negligible, going off memory of my attempts to review the literature. I still resent the expense, small as it is in absolute terms, plus the dependence itself. I've found that I can cut down on total intake by opting for weaker juice, but that has little effect on the parameters I care about, which are the money spent on the habit, and the addiction itself. It's not in the top 10 things about my life that I need to fix, though I'm grateful for the words of encouragement.

(I knew the theoretical health risks were small, when I initially started. I had avoided cigarettes like the plague itself for most of my life, but I was curious about vapes, which were hard to get in India. When my ex and I landed in London several years back, we ended up locked out of our Airbnb on a cold night in October. We went to a gas station grocery store for food, where I spotted a vape. I wanted to buy it, but my ex was a cancer survivor and was scared of the risk. Being the nerd I am, I sat her down, and we went through multiple systematic reviews while eating a chicken sandwich. Eventually, we concluded that the risks were minimal, especially the carcinogenic potential, and with her assent, I ended up buying one. Still, #BlameGwern.)

Tapering off with weaker juice is the way to go. Once you go from 3mg to 0mg it's a case of a few days of habitual puffing until you think "wait, why am I doing this?" and will stop very easily because there's no longer a deficit demanding to be replenished. After that there's no more addiction and no more expense. Problem solved.