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That's the thing though, no doctor has explained to me why it's over for things like radical bone thickness changes. Growth plates determine longitudinal growth, but there's no hard reason why bones can't get radically thicker post-puberty. Especially if, as you say, you intake some kind of research chemical. Or even just plain old HGH.
I'm pretty sure it comes down to hormonal environment. Maybe some kind of epigenetic signaling occurs when growth plates close? Because there's no mechanical reason your wrists can't get inches thicker anytime, as far as I know.
It's been a year or so since I had an MRI but it showed areas of defused bone where the growth plates are, low-intensity signals that are wider than they're supposed to be from comparing. Nobody remarked on it because it's not a full ass growth plate. But I have managed to DM a couple of orthopedic doctors on reddit and they confirmed it might be unusual to have such width of low-intensity signals at the growth plate scars, although not something anyone cares about.
Probably the growth plate fusion happened already but, like the rest of my bones being osteoporotic from starvation during puberty, it's not a tight seal, and the scar contains some (relatively to average, but may or may not be clinically) significant remaining cartilage.
Hence I wonder if the epigentic signaling that occurs when growth plates close, just didn't happen for me, and I'm in some weird never-went-through-puberty (I did briefly, before ending its progression with starvation) hence never-fully-matured state. It may be that with the right dose of lifestyle or chemicals, those plates have two trajectories possible: full fusion, with a tight seal, from the continued influx of resources, or somehow with the hormonal and lifestyle ingredients being just right, the cartilage might proliferate. Starvation is bad for you but it does retard your biological/skeletal age. I'm only getting chest hair now when my father got it at 19-20.
I do have lifestyle factors I need to fix to get stronger physically, and I believe I can get a lot of improvement from that. But I do want to fix my fundamentals if possible. My wrist is 1st percentile for women, but I'm around 15th percentile overall body size for men. That's a mismatch, maybe it doesn't matter that much, but it would be nice to correct it.
I'm not a doctor, but I bet an LLM could answer most of your questions around this.
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