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Friday Fun Thread for September 25, 2026

Be advised: this thread is not for serious in-depth discussion of weighty topics (we have a link for that), this thread is not for anything Culture War related. This thread is for Fun. You got jokes? Share 'em. You got silly questions? Ask 'em.

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Unbelievable effect sizes. Are you willing to make a bet with me that those won't hold if you correct for cross sectional confounders? Where you take the position that the positive effect will hold. Or are we just making performance here? Do we really believe that something that shreds DNA has such a ridiculous dose-response curve?