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Culture War Roundup for the week of July 24, 2023

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Since my 'don't trust Science' threads were already toeing the line between 'Pepe Silvia!' and schizophrenic (fair!) (I didn't even touch the four-part follow-up), Nate Silver summarizes better than I can :

Here’s the scandal. In March 2020, a group of scientists — in particular, Kristian G. Andersen the of The Scripps Research Institute, Andrew Rambaut of The University of Edinburgh, Edward C. Holmes of the University of Sydney, and Robert F. Garry of Tulane University — published a paper in Nature Medicine that seemingly contradicted their true beliefs about COVID’s origins and which they knew to be misleading. The paper, “The proximal origin of SARS-CoV-2”, has been cited more than 5,900 times and was enormously influential in shaping the debate about the origins of COVID-19.

We know this because of a series of leaked and FOIAed emails and Slack messages that have been reported on by Public, Racket News, The Intercept and The Nation along with other small, independent media outlets. You can find a detailed summary of the claims and a copy of the emails and messages here at Public. There’s also good context around the messages here (very detailed) or here and here (more high-level).

((Silver's links carry the touchstones of conspiracy paranoia, like an emphasis on coverups and literally-by-the-minute analysis of claimed coordinated action, which would normally discourage me from pointing to them, except they also happen to be reasonable factual descriptions.))

To be clear, this isn't a case of some barely-related scientists from nearby offices in slightly-related fields being somewhat more open-minded. These documents demonstrate each and every single author of the paper held some of the exact same concerns about the proposed wet market origin as piles of shitposters and too-online dogs, often pointing to the exact same evidence... privately. In public, they named opponents giving these possibilities conspiracy theorists for naming options they were accepting privately, or drawing out a web that actually existed. Jeremy Farrar would send e-mails giving 50:50 odds on natural (and non-natural, mostly serial passage) origins at the same day he was shopping around early drafts of the paper; while he isn't on the author list, that's its own mess. To be fair, they do change positions in private, as information comes around and as debate occurred. But they remain far from as convinced as they pretended in public, not just during publication but months later, and it's exceptionally clear that the political and pragmatic ramifications drive that.

Nor was this filled with caveats and used or intended to be used solely as a small opinion piece. It contains a few limited cautions about available data's ability to discriminate from evolution at the wet market from cryptic adaptation among humans, but serial passage was actively dismissed by an incoherent mush that steps from animal models to purely in vitro considerations. The paper's authors and 'unrelated' academics (who had been heavily involved in discussions with the paper's authors behind closed doors) cited this not-a-paper at length to justify treating anyone even considering the possibility of just serial passage or an accidental lab leak to be a conspiracy theory that must be shut down, all the way from casual shitposters to federal politicians, including those who advocated specifically serial passage or a purely transport-focused accident. These private messages make clear that wasn't some unintentional side effect, but a if not the specific goal.

Nor was this limited to the broadest strokes: at best, these otherwise closely-knit scientists did mention important information not widely available to random shitposters to each other, such as the rarity of live pangolin trafficking, or the animal makeup of the wet market's official shipments, or a variety of information about possible serial passage techniques, all of which were carefully excluded from the final paper. Some writers received confidential notice of discovery of RmYNO2, and after finding that it wasn't itself more helpful to their point than other already-known genomes, decided to instead obliquely reference it as possible to make a 'prediction', because the Texas Sharpshooter's approach would have been too on the nose.

And that's the stuff that came through FOIA-able emails or broad and leakable Slack channels. The messages show many people involved transitioning to private e-mails, to phone calls, to unrecorded Zoom meetings, often dropping to very clipped wording during that transition: they knew this could eventually be public, and they knew other conversations would not.

None of this amounts, as many COVID skeptics are calling it, to research fraud; I'm not even sure it fits most definitions of academic misconduct. But that's mostly because the publication didn't have enough numbers or analysis to need to actively lie: this paper has no pixels to check for signs of photoshopping, nor specific population numbers to hit with GRIM. Silver has joined calls to retract the paper, but Nature's staff have already said that "Neither previous out-of-context remarks by the authors nor disagreements with the authors’ stated views, are, on their own, grounds for retraction." It ain't happening.

Silver proposes that the scientists were motivated by some combination of :

  • Evidence of a lab leak could cause a political backlash — understandably, given that COVID has killed almost 7 million people — resulting in a reduction in funding for gain-of-function research and other virological research. That’s potentially important to the authors or the authors’ bosses — and the authors were very aware of the career implications for how the story would play out;
  • Evidence of a lab leak could upset China and undermine research collaborations;
  • Evidence of a lab leak could provide validation to Trump and Republicans who touted the theory — remember, all of this was taking place during an election year, and medical, epidemiological and public health experts had few reservations about weighing in on political matters.

These aren't exactly the most charitable framings for each possibility, if perhaps more charitable than focusing on Anderson's certainty this paper got him tenure. But with a more forgiving description, I get something along the lines of :

  • Prohibitions on gain-of-function and other virological research could undermine pandemic responses (and we wouldn't know about past prevented pandemics, after all), or drive research to locations with worse biosecurity or oversight (than BSL2?).
  • Bad relations with China could undermine future pandemic responses or escalate to a 'hot' war.
  • Trump and Republicans responding to a China with marginal scientific research could result in another Korematsu, undermine future pandemic responses, or escalate to a 'hot' war.

Perhaps @Chrisprattalpharaptor can do better. But even if these somewhat earnest reasons that business or political tribe might have controlled what these scientists were willing to say publicly, or if there was some more noble cause that they held above providing an accurate model of the world, it's still something other than providing an accurate model of the world. Which is what, supposedly, was their job.

Worse, few of these matters stop here. Trivially, a lot of academics and casual observers are saying that even if the Nature op-ed authors were playing fast-and-loose with the facts at the time, we since have a ton of evidence in favor the wet market/natural origin side and very little recently published in favor of serial passage or any intentional manipulation, and normally drawing big charts claiming almost all the experts in a field were conspiracy to hide The Truth would be the sorta thing you do shortly before the nice men give you a coat with extra-long sleeves and take you to get some anti-psychotics. Except all of the above.

The guys who authored the paper testified before a maximally hostile Congress last week. I was ready for them to get torn apart and surprisingly it left me less convinced of the criticisms against them.

The pangolin thing, as covered by the Public Substack and other places I've seen it repeated, seems to be misframed. The scientists never claimed that it was the actual origin of Covid; they explicitly says it's a different virus, just similar in structure. The argument is that no one (including any of the lab leak proponents, to my knowledge) seems to think the pangolin coronavirus variant, 600 miles away from the Wuhan lab, was also man-made, which raises the odds that a virus very similar to Covid-19 could arise naturally.

The distance in time between the scientists saying they weren't certain about how something like the Receptor Binding Domain in Covid-19 could manifest in nature, and them changing their minds and publicly supporting a natural origin theory, wasn't an abrupt turn around of a few days, as alleged, but rather forty five days. During that timeframe the pangolin samples with similar RBDs were discovered, raising odds that this kind of thing could be naturally evolved. In contrast, the site being studied in the EcoHealth proposal was genuinely different than that in Covid-19.

Beyond that, the main thrust of their argument is that the first samples were found in the Hanan market and the first cases in the area surrounding the market, not in the areas surrounding the Wuhan Virology Center. As far as I know nobody has contradicted this, though I don't really follow it and could be wrong.

I think the concerns about how the process was politicized, especially by bueaucrats worried about conflict with China, are still valid - welcome to government though. Claims of a vast Orwellian conspiracy on part of our neoliberal overlords I think are a little unconvincing given that our government has also argued that it probably was a lab leak. In fact, right now six agencies have weighed in and none agree - the DOE and FBI think a lab leak was most plausible, four other agencies plus the NSC suspect natural origins. Almost all of them have framed their results with "low confidence," but you can pick whichever result you like and still say the government agrees with you.

I personally consider the lab leak somewhere between possible and likely, but don't really care where Covid came from. Even if it was caused by research conducted by China and America, the two most powerful countries on earth are obviously not going to pay any kind of penalty.

I think the concerns about how the process was politicized, especially by bueaucrats worried about conflict with China, are still valid - welcome to government though

I think the issue is the effect the politicization has on scientists. Just saying 'welcome to the government' sidesteps the whole point.

The scientists never claimed that it was the actual origin of Covid

OK, but any other theory was called a conspiracy theory (at best). So they put forth one possibility and suppressed anything else... You don't see a problem here? It's the theory version of 'You can have a model T in any color, as long as it's black'.

The distance in time between the scientists saying they weren't certain ... but rather forty five days

The world is a big place, 45 days isn't slow. And again, look at how other ideas were treated. Look at how youtube and twitter reacted to people floating different ideas. It's very easy to focus on the people shooting at 5G towers but that ignores actual doctors and scientists who were labeled racists for saying it might of come from a lab.

The world is a big place, 45 days isn't slow.

The claim on the part of the skeptics is that the scientist made an abrupt 180 on their views in only a few days because of pressure from the NIH. Instead they had a month and half during which relevant research was published that overturned the main cited uncertainty.

OK, but any other theory was called a conspiracy theory (at best). So they put forth one possibility and suppressed anything else... You don't see a problem here?

This is what the scientists had to say about the lab leak theory vs the market:

As many early cases of COVID-19 were linked to the Huanan market in Wuhan, it is possible that an animal source was present at this location....

Although the evidence shows that SARS-CoV-2 is not a purposefully manipulated virus, it is currently impossible to prove or disprove the other theories of its origin described here. However, since we observed all notable SARS-CoV-2 features, including the optimized RBD and polybasic cleavage site, in related coronaviruses in nature, we do not believe that any type of laboratory-based scenario is plausible. More scientific data could swing the balance of evidence to favor one hypothesis over another.

Pretty reasonable imo. Anyone is welcome to dispute their scientific claims. Again, the same government you're accusing of supressing the lab leak has also repeatedly endorsed the lab leak. Seems like a pretty sloppy coverup imo.