Grant_us_eyes
No bio...
User ID: 1156
Grant_us_eyes
16hr ago
Fair disclaimer; the links and exerts were from an effortpost I put together(but never posted), and when I went back later to double-check some information, found that the article was now behind a paywall. Of cource. I hate this fucking timeline.
So if you don't believe any of said exerts and call me a filthy fucking liar, the most I can do is shrug, cause I don't really blame you.
Solving cancer via LLMs and mRNA vaccines is already done and established science.
Kinda.
With 17 years of experience in machine learning and data analysis, Mr Conyngham is an AI pioneer – an electrical and computing engineer who co-founded Core Intelligence Technologies, and was a director for the Data Science and AI Association of Australia. Once UNSW handed him the genomic sequencing, for which he paid $3000, he got cracking to decipher the data.
The genomics team reached out to Pall Thordarson, director of the prestigious UNSW RNA Institute. A pioneer in nanomedicine, the Icelandic professor used Mr Conyngham’s data, crunched down to a half-page formula, to create a bespoke mRNA vaccine for Rosie. [...] What Professor Thordarson finds most remarkable is that a data engineer with no background in biology managed to generate the mRNA recipe.
Now, we all know about mRNA vaccines(cough cough Covid cough cough), and while their efficacy is... I'm sure, debatable and contentious. But in this specific instance, it at least had results;
“It’s definitely working,’’ Professor Allavena said. “When it happens that first time, it’s magical. Rosie’s cancer was really, really advanced but one tumour has shrunk quite a lot – probably halved. Even though it hasn’t completely disappeared, she’s so much more comfortable because the tumour was so big, and now the cancer’s shrunk away. Even the glossiness of her coat, she just looks a lot happier and healthier." [...] Rosie’s recovery has been a howling success, with most of her tumours appear to melt away in a matter of weeks. [...] Rosie’s devoted dog-dad is now working on a second vaccine targeted to attack one large tumour that did not respond to the initial treatment. The UNSW scientists started work on the genetic sequencing this week.
Again, not a magic cure-all or panacea, but sometimes you have to appreciate that the pig can dance at all.
However, turns out you don't need LLMs at all;
Sorry to be the downer because this is an impressive story in some senses. But it is ~trivially easy to make a single mRNA vaccine. It's not hard. I cure mice of various cancers with various therapeutics all the time. I've made mice lose more weight in a month than tirzepatide does in a year. What is hard and expensive is proving its BOTH safe AND effective in a randomized and controlled study in humans while ALSO manufacturing it at clinical scale and grade. I am happy for this man and his dog. It is impressive. But y'all are overhyping it.
(Emphasis both removed and added from the original.)
And, even better;
I literally have an ongoing cancer experiment where 100% of the untreated and control animals have had to be euthanized while 100% of the treatment animals are seemingly unaffected. But we're still extremely far away from "proving that it works." Science is hard.
(Emphasis added.)
Note: I am unable to check the twitter links for the above, as my account for twitter has been locked out barring cell phone verification, so I cannot confirm they work or link to what they say anymore.
I hate this fucking timeline.
So, mRNA cancer solutions are already a thing, but we can't have them, for reasons, I guess.
So the real question we should be asking isn't 'Can we do this', cause we already do. The question should be 'Do we trust Anthropic not to fuck things up' and I think I know what my answer is.
Grant_us_eyes
2d ago
I typically abhor any kind of seltzer water, but I've found I have a very specific taste for Topo Chico's Lime and Mint. Very refreshing, no sugar/sweetener, zero calories.
Grant_us_eyes
3d ago
Ah, skimmed over the review-bombing portion. A fair opinion.
I confess to being just a tad thin-skinned about the topic, as I've found people who bring up the entire 'GFL2 Chinese gatcha players' tend to run either toward casual bigotry and/or the kind of people whom would be making fun of nerds back in high school, with a strong whiff of grifting/tourism 'how do you do fellow gatcha players'.
Still, like I said. Understandable, coming from your PoV. Admittedly, I haven't played Reverse Collapse, mostly due to my first exposure being GFL and knowing how, uh... look, I know how these guys go in their writing. It's good stuff, don't get me wrong, but there's only so much existential depression I can take.
Grant_us_eyes
3d ago
Another fact, apparently Chinese gacha players got angry that in GFL2 a female character has close relations with a male NPC character that they felt they were being NTRed because only the player should have any sort of relationship with their gacha waifus so they review bombed Reverse Collapse instead. Chinese gacha players seem to be a different breed entirely.
It's a bit more involved that this; the character in question was from GFL1 and represented the QBZ-14 rifle - which, for those not in the know, is the national rifle of the Chinese army, so there's a bit of national pride involved there. Second, when the company that owns GFL took a look at the matter, resulted in an official statement involving potential corporate sabotage, atleast one fired(female) writer, and a flood of original writers coming back from working on thier side-project Project Neural Cloud and noting a marked increase in writing quality from the early game in GFL2 to the current.
So there's a bit more teeth there than just 'blooh blooh chinese weebs are weird fucks'.
Grant_us_eyes
8d ago
Dandyism has entered the chat.
I have weird obsessions, okay? I only wish I had gotten that book when it was new, as opposed to now. That price tag, yikes...
Grant_us_eyes
11d ago
Very true. I’m just trying to point out that, while I one among many with issues regarding Darwin, I don’t recall him ever using Llms to try and back up his arguments.
Grant_us_eyes
11d ago
I... I'm sorry. What? I cannot even begin to fathom how someone could come to this conclusion.
I'm not being disingenuous, or anything like that. If you have any articles and/or references to point me at, I'd love to read them.
Grant_us_eyes
11d ago
? This is a common rhetoric that's often seen on twitter. As much as I hate defending Darwin, he kinda ghosted before referencing LLMs as some arbiter of reality became very popular.
Grant_us_eyes
13d ago
Using LLMs for artwork is a very interesting case of economic forces in action.
Turns out, it's entirely possible that alot of artists are simply pricing thier results too high and are getting bit because of it.
Grant_us_eyes
22d ago
Really hard to beat The Devil's Spear. That sheild drop moment is just utter perfection.
Xcancel stopped working a few days ago due to them being sued by X, but I’ll try the alternate instances later. Or just give up and install the nitter extension. Thanks for the links.
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