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Inflamed_Heart_Liberal


				

				

				
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joined 2022 September 05 17:30:11 UTC

				

User ID: 648

Inflamed_Heart_Liberal


				
				
				

				
1 follower   follows 0 users   joined 2022 September 05 17:30:11 UTC

					

No bio...


					

User ID: 648

I want to make a separate point to bring up your blue tribe distinction.

Every time Covid-19 vaccines come up, very low level "pro-vax" discussion starts occurring. I see extremely washingtonpost or Foxnews tier discussion of these products.

If you check my post history, I have a complete throw down against the mRNA products. Currently, the pro-vax perspectives coming in this thread could have been completed by Reuters fact checks or some other political organization.

So, I offer the following:

  1. Astroturfing in the provax camp is occurring on the Mott OR

  2. Only less educated, less biologically inclined 'pro-vaxxers' are appearing in these threads with years old talking points and critical obfuscations of what happened during the mRNA / adenovirus vaccination campagin.

  • -16

Inaccurate. If you look at the mRNA vaccines in particular, they can cause a heart condition that can cause death. Its a well recognized condition called peri-myocarditis. Are those deaths worth protection from covid? That's the argument that's falling apart right now.

"Lingering effects of novel viral illnesses have been well-documented" Did you mean to use the word novel? There are lingering effects possible of all viral illnesses, not just novel ones. I would not compare this to Spanish Flu, compare it to The Russian Flu/Corona of 1800s..

The idea that nascent respiratory infection would have killed someone that had a "mild" reaction to the mRNA is completely unsupported, and conveniently forgets the introduction of the novel nanolipid particle that delivered this first generation vaccine.

https://pubmed.ncbi.nlm.nih.gov/36436002/

So the vaccine can make you die in a special way due to lymphocytes in your heart - but the idea that Damar did not have any type of underlying structural sensitivity to a tackle is completely debunked...I do not think so.

While it may not be appropriate to call it astroturfing, I wanted to point out that it is uncommon to see a detailed pro-vax analysis on the motte. It uses very quick "off lamps" that are supported by fact checking / expert trust / credentialling institutions.

Rather than say AstroTurf, I'd say there is a peppering of shallow, short cut arguments that never develop fully into an authentic, organic long form idea.

Agreed, I will be much more careful to use a short cut like that, and avoid needless linking to an outgroup that's not the main topic of my concern.

Good point, Sweden is doing well despite giving the mRNA vaccines. I'm happy you found a single western country that used mRNA and is not experiencing a precipitous increase in death. And they have excellent foresight to avoid giving risky vaccines to children.

https://www.reuters.com/world/europe/sweden-decides-against-recommending-covid-vaccines-kids-aged-5-12-2022-01-27/

I know Sweden acknowledges that the risks of the vaccines are only useful when comparing against the risks of the virus.

"Conspiracy theorists." Why are you drawing conclusion on a single countries demographics? This is not a good faith accusation to people who are worried the novel mRNA vaccine is causing unnecessary morbidity and mortality, even Sweden has decided to stop putting children at risk. Is this responsible for their better mortality statistics? Hard to tell but I know you need to update your priors here.

There is a radical difference in allowing 5 year olds, and 12 years olds, to receive nanolipid particle injections. And you failed to mention that.

Um no.

https://pubmed.ncbi.nlm.nih.gov/36436002/

Here's a scientific paper showing there is a special link between mRNA and sudden death. Why would the right not be interested in the counternarrative developing? It's a smoking gun.

https://pubmed.ncbi.nlm.nih.gov/36436002/

I mean, in many ways, people keep proving that a safe and effective vaccine is actually dangerous in ways comparable to a "dangerous" infectious disease!

Why are autopsies finding out that the heart is participating in the vaccination process! We should see lymphocytes in the muscle of the deltoid, not the heart.

https://pubmed.ncbi.nlm.nih.gov/36436002/

I am spamming this and I apologize to anyone who's mad about this. We can find evidence of special heart damage from the mRNA vaccine from autopsies. We have the FDA announcing a possible association with PE and Pfizer. This nurse could simply think "I've seen a slide of someone's damaged heart after vaccination, maybe it's connected." and all of a sudden you accuse them of a crime of logic.

"Electronic databases (MEDLINE, Scopus, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and the WHO Global Literature on Coronavirus Disease) and trial registries were searched up to May 2022"

This is old data now, and every single undetected case of Coronavirus during that time period was not counted into that rate. This is what all the health authorities used to make light of the heart damage that mRNA can cause, just like you are doing now. There's incidentally been hundreds of millions of natural infections since then, undetected, making the rate of myocarditis by covid essentially become asymptotic to 0 as everyone becomes naturally immune, possibly twice.

https://pubmed.ncbi.nlm.nih.gov/36436002/

Here's a post-mortem that shows the same WBC in your injection site, infiltrating the tissue of the heart and causing sudden death. You must not keep up with Pathology journals about people found dead after the mRNA vaccination, or they're not talked about or published in your countries.

"The relative risk (RR) for myocarditis was more than seven times higher in the infection group than in the vaccination group"

Even at best: you're telling me we are giving a vaccine that causes heart damage, only one order of magnitude less than a novel clade of beta-coronavirus that spilled out so fast we couldn't even count all the cases? And that's a good thing?

Well, let's say you did not want to take the vaccine, and you were mandated to take it. You could choose either J&J, mRNA, Novavax, or even fly overseas to get Covaxin. You may begin debating at that point.

mRNA vs. Other vaccines is a very difficult topic, because defanging a countries ability to give mandated vaccines is bad, but mandating vaccines that are bad isn't good. In fact, perhaps extreme caution should be taken based on the prior.

I am much more worried about real, physiological implications of nanoparticle technology uptake. Not simple safety standard concerns (those already seem tattered).

I can't lead you further to water than this. I have evidence that there is a virus recirculating, not circulating for the first time. The same way vaccine reduces myocarditis, so will infection with natural immunity. Except the vaccine also causes myocarditis: thus our impasse.

A new New York State Covid-19 Dataset was released a few days ago. I thought it was a good opportunity to see the progress of the vaccination campaign. I think it's great data for an attack on the performative ritual of getting 'vaccinated' to encourage others to get vaccinated as well (which is what a lot of people were convinced to do). Obviously, those who got vaccinated to "protect other people" stand on shakier ground now.

https://www.governor.ny.gov/news/governor-hochul-updates-new-yorkers-states-progress-combating-covid-19-467

First, let's establish something important. mRNA vaccines have a established, not fully understood connection to peri-myocarditis. mRNA can cause heart damage in a way that other vaccines seem to avoid. I would say this is an important explanation for the following data:

Percent of New Yorkers ages 18 and older with completed vaccine series - 85.5%

We all know how this was done. OSHA directed mandate, NYC mandate, banning people from shows, restaurants, bars until they receive an EUA injection, healthcare worker mandate, bribing people 100$ a shot. Science communication and incentives couldn't get people to take a novel vaccination method. NYS is almost 20% unionized, and the mandate was really helpful in boosting the low minority vaccination rate, since so many of those individuals work unionized, mandated jobs.

Now that these incentives are gone, let's see what the uptake is:

**Percent of all New Yorkers who are up to date - 14.1%

**

Most New Yorkers ignore CDC guidance now. Covid-19 will be gone in a few years. Covid-19 will be retired as a word for "novel entry of pathogen SARS-2," SARS-2 will be renamed HC-391237 or OC-32871 (random examples) or something, and the "covid-19 vaccine" will be rightly seen as a genetic version of a "flu shot" like intervention.

Consumers who want "flu shot" like vaccines, will eventually come to prefer conventional, protein adjuvanted vaccination methods.

Why would a 19 year old ever get an mRNA injection, when they could get a shot of Covaxin? The main purpose of the shot being to end the harassment from the public health infrastructure, and gain employment or education.

**Percent of New Yorkers ages 0-4 with completed vaccine series - 7.9%

**

This makes me think the vaccine could be seen as dangerous to parents. Keep in mind that all high-risk (on ventilator) children have probably been vaccinated, but some likely have not.

The vaccine campaign was a performance. Young healthy people were asked by the CDC to pretend that genetic Covid-19 vaccination was completely benign and well understood, with the goal of ultimately getting high-risk patients to take the higher risk vaccine.

If 20-29 year olds were allowed to say "no, that vaccine causes heart damage, obviously not worth getting," skepticism would trickle up to individuals who should arguably take advantage of the more advanced vaccination method. May the benefits outweigh the risks. No one believes in "do no harm" in the age of state-mandated genetic injections.

Since you can die suddenly from dysrhythmia after vaccine induced myocarditis, we need to reevaluate where we are in this campaign. This was not known at the EUA authorization in 2020.

Yes, the evidence is the nature of how effective natural immunity is compared to the vaccine induced immunity, which wanes. You will receive the protection of the vaccine, and more, if you get natural immunity, therefore your next encounter will have a reduced magnitude compared than if you had just the vaccine alone.

I feel like you're fishing for exact, quantitative data - I need you to be patient as data about our current times is collected. I'll have evidence to back up thr natural immunity claim in the future, just like we saw develop in 2020-2022. This is a developing emergency, that the vaccine has had some malfunction / additional risks of heart problems that are only being discovered recently. I wish I had the long term data of our developing vaccine emergency NOW, but that's simply not an option. I'm happy you agree with my overall hypothesis though.

This is not the right take.

You should be much more concerned about the size, shape, and ability to move through your body compartments with a Vaccine, than with a virus entering your mucosa.

The virus, if anything, is very limited by ACE2 receptors, whereas the lipid nature of the mRNA droplet allows it to merge into literally any cell and make it into an antigen producing cell. Much more than ACE2

This is not all proven - the vaccine entering body tissues because there's no known characterization of nanolipid particle pharmacokinetics is the main issue her. There's no concentrated ACE2 receptor in testicles, but the nanolipid particle will be exposed to the testicles via the blood stream (at the testicle blood barrier, which the vaccine can cross).

The vaccines are dangerous precisely because we are analyzing and looking for hidden harm, after we already administered a billion doses without fully understanding the consequences and outcomes.

mRNA cardiovascular toxicity is a severe problem and if it's at all likely, the hammer should drop. This "blip" is an 18 year old about to get mandated with mRNA bivalents before going to a community college.

That hardly explains why the same lymphocytes at the deltoid vaccine site were found in the cardiac tissue. It was a specific immune related reaction.

https://pubmed.ncbi.nlm.nih.gov/36436002/

Why are hearts found with heart damage in cadavers? Why is it not plausible that this is a actual issue?

The online right is, alternatively, demonstrating the exact appropriate amount of interest you'd expect, countering the efforts of a public health campaign to minimize this information.

(1/2)

Yes. Let's begin. I apologize for my lack of formatting, you're right, it was meandering.

Be careful drawing facile conclusions from large correlational studies like this. And not to be a paternalistic douchebag (feel free to ignore if you know better) but you might find it helpful to skim the discussion of a paper if you aren't familiar with the field to at least get a feel for the limitations or alternative explanations of the study.

Yes, there is a complete heterogeneity of the population at this point. I understand the point, and I appreciate you walking through more of the PE risk benefit. I am relatively familiar but didn't enter the weeds. I agree this is a correlational study. I am aware of the authors explanations and limitation.

They are forced to use historical data.

They are forced to use the worst possible CFRs when we had the least tests available and the fewest eyes on the spread, compared to a disinterested, uninformed group of clinicians who would have been responsible or detecting vaccine side effects. We need pathophysiological studies and autopsies - once again extreme lack of interest in autopsy for vaccine recipients. The data is muddled, so we need firm exploration into underlying mechanisms and gaps in our understanding of mRNA vaccines.

Let's look at other studies that show problems with mRNA. I can't link them to PE myself, you need to take your pathophysiology knowledge with you into this exploration.

There is a suspicious group of studies that cast extreme doubt on the basic functioning of the mRNA vaccine as an antigen producing unit that remains in the deltoid.

Usually sudden death after vaccination would be related to anaphylaxis due to an allergy to some vaccine component, whereas the myocarditis takes a few days to develop.

First, in my healthcare facility, Anaphylaxis was less than double the increase from traditional vaccines. I would say mRNA performed very well in the realm of anaphylaxis (remember, allergic reaction 2 body systems and life threatening). I have suspicion that mRNA is responsible for allergic generation issues (e.g. anecdotal bilateral hives after vaccination) but I have no evidence. I just know that mRNA spreads its antigen creating goodness throughout the body, at a frightenly common rate. If you see sudden death as a possibility of anaphylaxis, you may be mistaken in some ways.

I am surprised you are unfamiliar with https://pubmed.ncbi.nlm.nih.gov/36436002/, Autopsy-based histopathological characterization of myocarditis after anti-SARS-CoV-2-vaccination.

Note lymphocytic infiltration of cardiac myocytes (I won't even continue on with the arrhythmogenic implications of this permeant heart damage, a.k.a. died suddenly). Yes, vaccines are supposed to enter your lymph and lymph node, but your lipid nanoparticle has different pharmacokinetics, and seems to pass the lymph nodes and enter your blood stream, whereas my J&J virus does not. This is a huge win for me, over your choice of vaccine. Let's see - deltoid goes to lymph vessel, lymph vessels carry mRNA to lymph node, some of the trillions of mRNA baubles awash past the lymph nodes and get dumped into venous circulation (right before entering the Right Atrium of the heart). This is all done before even getting a pass at the liver.

Yes, I think a bad football tackle can exacerbate the exact underlying pathology that was discovered in the German Pathology Autopsy reports. Entirely plausible.

J&J has a form of tropism to enter cells, wheras mRNA is enclosed in a non-tropic lipid droplet that can fuse with the phospholipid bilayer of much more than just a muscle cell. Lymph vessels are a one way valve that do not require deposition of mRNA payload to enter lymph circulation (then subsequence blood stream circulation.

Did you know the lymph is responsible for distributing dietary lipids to your blood stream? Are you concerned that you took a novel lipid and entered it into the system that transports macronutrients? The early applications of lipid nanoparticles were as oral form blood pressure medication. Why? The lipid nanoparticle is great as distributed systemic effectors. Your vaccine distributed mRNA as if it was a beta blocker.

The mRNA vaccine is found in breast milk: https://jamanetwork.com/journals/jamapediatrics/fullarticle/2796427. mRNA enters the blood stream at a rate higher than other vaccines.

Spike protein is in blood stream of myocarditis patients. https://pubmed.ncbi.nlm.nih.gov/36597886/

I don't think spike protein is the issue, but the signal that the antigen is in the blood stream. What exact tissue was the antigen created? Probably not exclusively in the deltoid myocytes.

There's plenty of papers: Here's a review that will have a summary and a couple dozen primary references if you're interested. Many primary papers investigating the mechanisms as well.

Thank you. Looks like the etiology of blood clots from Covid related PE would be different from an mRNA related PE, so we need to be especially suspicious of the signal that the mRNA vaccines could cause a PE. Especially since historical data has to be used due to lack of long term safety monitoring before mass vaccination. If severe flu can cause PE, I'm extremely unmoved by severe covid causing PE. Viral pneumonia sucks and too bad antibodies can't hover inside of your parenchyma and actually generate a sterilizing immunity.

Since I will not be getting Covid Viral Pneumonia, I am very interested in the chance that this "routine medical procedure" can cause PE.

The last time I looked into myocarditis it was vanishingly rare, a tiny number of deaths were attributable to it and those individuals seemed to have many other medical conditions.

the authors report zero deaths associated with vaccine-induced myocarditis

This is a horrible sign for your data, since I've seen the slides of lymphocyte aggregation in the deltoid of a cadaver, as well as in the heart of a cadaver after vaccination. What do you think of this discrepancy? This is an 11 month old reddit post, the autopsies were not completed then. I think it makes your data look unusable. As a counter to the redditor - maybe this is CIA propaganda to make the vaccine seem safe, to counter Russians propaganda to make you think the vaccine can kill you (which the Germans actually proved was true). This was all in the reddit post you linked to - not an unrelated sneer.

https://onlinelibrary.wiley.com/doi/full/10.1111/eci.13947

Yeah admitted self own, this is the Prasad paper, which paints a stratified risk that is not vanishingly rare. I'm not pushing this more than my above point.

As well say this for tetanus, flu, rabies or any of the other viruses we need boosters for. Immunity wanes particularly quickly for respiratory viruses. Note also that the Moderna booster is a half dose, so modulo some weird memory effects likely has lower rates of adverse events.

Come on. None of those vaccines involve mRNA lipid nanoparticles. Getting boosted with mRNA to seek antibody titers is aboslutely not the same thing as getting a tetanus booster in 10 years.

I mean this is a very very polite way - how did you find your way to the Motte? You started strong, but these are common misdirections on the exact argument - mRNA is a special novel biotechnology, stop mentioning vaccines that the market overwhelmingly accepted, and has centuries of application in the exact antigen deliver method (protein adjuvant). Have you ever mix and matched a measles vaccines in a year? Even when no data existed on it? Pfizer admitted you should not mix and match Comirnaty because of lack of data, you can only mix and match the EUA product. Which is...something...

I don't think we know the risk of myocarditis after reinfection; it's almost certainly lower, but I could only find two case reports so it's difficult to draw any conclusions or calculate the relative benefit of vaccination. Moreover, tens of thousands of elderly patients die of flu every year, and I can guarantee you that they aren't immunologically naive. Natural immunity isn't a silver bullet.

Okay, you agree with me, its certainty lower. Yes, I think it would be nice to distribute vaccines to elderly patients who are vulnerable. Is this why the FDA is vaccinating pediatrics? This is just a vacuous talking point. You just called Covid a flu. Why would you get the experimental nanoparticle for "just a flu bro."

I'm not sure I understand your point here.

It was not really for you. You seem to get it.

That being said, we've been infected by influenza for at least 1,500 years and it's still a major public health concern. A truly protective vaccine would be a major coup, and investing resources in these problems is worthwhile even if lockdowns and mask mandates are not.

Yes, more evidence that the entry of a novel, circulating respiratory pathogen into the population that targets elderly and vulnerable is entirely normal, see the Russian Flu in the 1800s. What's not normal, is becoming a fanatic for biotechnology.

The calculus for the vaccines was just much better early in the pandemic.

The calculus was "seek herd immunity." This involved minimizing the collapsed efficacy of the vaccine mid-distribution. Once again, you love comparing every known vaccine dose to every known covid case, when we absolutely know there is more infection than can be reported into the data. Then "severe disease and death."

My calculus is: the vaccine leaks into your bloodstream, and seeking protection from severe disease and death from one respiratory pathogen with a vaccine that leaks into your bloodstream is not advisable.

Inflammation from widely distributed nanoparticles. Look up inflammation, its complicated.

I guess that was part of the show. Vaccines were already so safe and bullet proof, people cannot notice when one that's 10x dangerous is released, and information censored online, and physicians told to be disinterested.

Novavax is a novel virus-like particle. I personally would much prefer Novavax over mRNA, and probably over adenovirus vectors.

I just don't like the threat of heart problems that mRNA presents. Such a large, dark downside to the products, to remodel your heart.

Agree with this.

I think Omicron is a large narrative tool.

Omicron is so much more deadlier than Delta because of its transmissibility, but this translates to less threat to each individual. I always grin when I see people "celebrating" omicrons rise, or remark how they avoided nastier variants, and now play host to the most transmissible pathogen in recent years. If you can catch a cold, once again, that means a 90 year old in a nursing home can catch it too.