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self_made_human  Grippy socks, grippy box  1mo ago (open.substack.com)   1589 thread views

Escaping the Jungles of Norwood: A Rationalist’s Guide to Male Pattern Baldness

open.substack.com

Out of enlightened self-interest, I did a deep dive into the topic of male pattern baldness, and after freshening up on my rather rusty Bayes', I decided that I'd gone to enough effort to justify a proper blog post. Here you go.

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Nice write up, in the last couple of months there was some researcher, this one i think? https://pubmed.ncbi.nlm.nih.gov/29569259/ , that claimed that some structural issue with a vein in the groin is the main cause for prostate cancer, and that the way it works is that it causes very testosterone rich blood go directly from the testicles to the prostate. have you seen anything related to that in your research? i did some googling after that because it sounded like something that could have at least an indirect link and havent found anything too clear, but wondering if you noticed something

It didn't come up, but I'm passingly familiar with what you're talking about. I believe that Scott has written about this a few months back, and the mechanism attributed was venous stasis/insufficiency causing the local hormonal levels to go too high.

Not related to balding as far as I'm aware, and largely out of my wheelhouse. I'll defer to Scott, and limit my commentary to saying that I don't see anything obviously implausible with the mechanism purported.

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