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self_made_human  C'est la vie  1d ago (open.substack.com)   556 thread views

A Depressed Shrink Tries Shrooms

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This is a first-person account from a psychiatry resident (me) enrolling in a clinical trial of psilocybin. Somewhere between a trip report, an overview of the pharmacology of psilocybin, and a review of the clinical evidence suggesting pronounced benefits for depression.

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Good post but bruh…

Frankly: I hate all this clinical trial bullshit around psychedelics and mushrooms. They definitely have anti depressive effects, but anyone that does drugs knows that the set/setting of these clinical trials is absolutely awful and retarded. You’re tripping and they just have you watching ig reels and tv?

Take 2 gs of real mushrooms and go for a forest walk and think about life. You’ll actually have some real insights about what’s making you that way. Treating these substances like just another pharma substance isn’t the way.

Drug prohibition is a crime against humanity!

I brought my own entertainment. The study design only offered "relaxing music" and an eye-cover if you were feeling overwhelmed. The music would have worked okay in an elevator or a Thai spa, but was absolutely not to my taste haha.

It's hard to blame them, really. Getting IRB approval for a clinical trial is a PITA on a good day, I strongly suspect that if they wanted to offer entertainment or a walk outside, they'd be raked over the coals, leaving aside the increase in liability and the demands on personnel. I'm certainly interested in trying shrooms in a more congenial environment!

Agreed, clinical trials are just a bullshit way to approach these drugs/medicines imo.

For you personally, yeah go on a forest walk and get into nature. That’s the real way to experience these drugs and most likely to have a positive life changing experience.

If you’re really ADD and need stimulation, maybe just go to a music festival then?

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