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self_made_human  amaratvaṃ prāpnuhi, athavā yatamāno mṛtyum āpnuhi  6mo ago (open.substack.com)   1599 thread views

A Depressed Shrink Tries Shrooms

open.substack.com

This is a first-person account from a psychiatry resident (me) enrolling in a clinical trial of psilocybin. Somewhere between a trip report, an overview of the pharmacology of psilocybin, and a review of the clinical evidence suggesting pronounced benefits for depression.

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Sorry, when I said triggered by pot I meant it made them (according to them) overly paranoid or dip into psychosis and they hated it. Isn't that what you meant when you said:

but the latter? If you have some kind of genetic predisposition, such as to schizophrenia, that will fuck you up

?

Ah, gotcha.

Cannabis can induce outright psychosis and initiation of schizophrenic symptoms in people with genetic vulnerability towards it. The higher the dose, the higher the risk.

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