This is a first-person account from a psychiatry resident (me) enrolling in a clinical trial of psilocybin. Somewhere between a trip report, an overview of the pharmacology of psilocybin, and a review of the clinical evidence suggesting pronounced benefits for depression.
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We don't really have a good idea how different individuals will react, this guy seems to have pretty badly f*cked up his life https://www.theguardian.com/us-news/article/2024/aug/23/us-pilot-magic-mushrooms-plane-engines (tldr pilot takes some mushrooms for depression, 2 days later is riding in the jump seat of plane [as a passenger, not flying the plane] has a bit of mental breakdown and tries to turn off the plane's engines to wake up, the interactions with the crew are odd and suggest to me more of a break with reality [could be due to the shrooms, or not, hard to say definitely] then a murder/suicide but ymmv).
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