This is a first-person account from a psychiatry resident (me) enrolling in a clinical trial of psilocybin. Somewhere between a trip report, an overview of the pharmacology of psilocybin, and a review of the clinical evidence suggesting pronounced benefits for depression.
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Good post but bruh…
Frankly: I hate all this clinical trial bullshit around psychedelics and mushrooms. They definitely have anti depressive effects, but anyone that does drugs knows that the set/setting of these clinical trials is absolutely awful and retarded. You’re tripping and they just have you watching ig reels and tv?
Take 2 gs of real mushrooms and go for a forest walk and think about life. You’ll actually have some real insights about what’s making you that way. Treating these substances like just another pharma substance isn’t the way.
Drug prohibition is a crime against humanity!
We don't really have a good idea how different individuals will react, this guy seems to have pretty badly f*cked up his life https://www.theguardian.com/us-news/article/2024/aug/23/us-pilot-magic-mushrooms-plane-engines (tldr pilot takes some mushrooms for depression, 2 days later is riding in the jump seat of plane [as a passenger, not flying the plane] has a bit of mental breakdown and tries to turn off the plane's engines to wake up, the interactions with the crew are odd and suggest to me more of a break with reality [could be due to the shrooms, or not, hard to say definitely] then a murder/suicide but ymmv).
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