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A Depressed Shrink Tries Shrooms

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This is a first-person account from a psychiatry resident (me) enrolling in a clinical trial of psilocybin. Somewhere between a trip report, an overview of the pharmacology of psilocybin, and a review of the clinical evidence suggesting pronounced benefits for depression.

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Only ever saw one guy using it. Young guy, 20-something. A place where I worked part time, one of the temp workers loading the containers. He stank, literally stank so bad I could smell him - I have somewhat impaired sense of smell. Apparently he washed very rarely.. and this was summer.

Later I learned he was homeless, living in a tiny garden colony hut he broke into and even though he could have washed, he didn't. Everyone hated him because he acted aggressive, sometimes talked to himself, kept pacing all the time, was unreasonable... and stank. About every hour he'd mix a kratom drink using a lot of various powders he had there and then drink it. I guess because the labor force situation being what it is, he kept working there for several months.

Once caused a fire alarm because he lighted up a joint or cigarette in the toilets, but the place was so shoddily run they didn't know who was the culprit and he got away with it. Not sure what caused the company to blacklist him eventually.. probably got in a fight with someone.

I really don't think his was 'initial high'. As far as I know, he was persistently agitated this way, which, even more than the smell, caused others to hate him. Maybe he was mixing something else into those drinks though.