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I mean, sure, if you have no imagination. But choo choo, here we go to the Neighborhood of Make-Believe.
Scenario 1: As a cost cutting measure, the Obamacare gene editing doesn't target specific genes, and fixes the narrow pairings that are causing the problem. They just bulk replace, say, 5-10% of everyone's DNA. That's the only way it scales cost effectively. The government contract to make it so goes to a "Minority Owned Business" as many do, and wouldn't you know it, some H1B colony just uses Indian DNA samples to make their gene editing templates. Next thing you know, everyone's kids are coming out just a little bit Indian.
Also it doesn't actually solve any of the diseases it was supposed to.
Scenario 2: The average African American IQ in America is something like 85? But that's the average. Imagine you uplift the IQ of the child of some congenital felon with an IQ of 75. Can you first imagine the very special hell that child now grows up in? I've seen a few his/hers/ours scenarios where a child of a previous spouse is leaps and bounds smarter than the new wife (and the "ours" kids), and the abuse heaped onto them by the less intelligent new spouse is wild. Below average IQ parents can be fucking savage to the high IQ children that end up in their care. Now imagine that at scale.
Scenario 3: Congenital felons again. There is a strong correlation between high IQ and low criminality, but it's not perfect. Imagine we uplift their IQ, but not their criminal dispositions? If you thought "We Wuz Kangs" is bad, wait till you've seen "We Wuz KHAAAAAAAAAAAAAAAAAN"
And now I'm reminded of a classmate in elementary school, the "gifted" class's perpetual troublemaker, who combined high IQ with even higher impulsiveness. At an age where most kids figure out they shouldn't do whatever random, impulsive thing crosses their mind because they'll get in trouble for it, and the rest figure out that they should at least put some thought into how to not get caught doing the thing before they do it, he couldn't even find the impulse control to do much of the latter before following his impulse. Instead, he'd just follow his impulse, get caught, then put his high IQ and high verbal fluency to work trying to weasel his way out of the consequences.
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Khan is definitely the civilisation-killer one, the one that (potentially) can't be fixed. But you're over-focusing on pre-existing criminal dispositions; it's entirely possible people will accidentally or deliberately introduce psychopathy via the "high-IQ psychopaths have higher income than high-IQ non-psychopaths due to doing white-collar crime and other exploitation" correlation.
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I mean, I’m picturing something like an extra 20 years of useful life, 10 years of not so functional life, and maybe an IQ gain of 5-10. I am not an expert but would doubt you could realistically get much more than this. Laying aside the race stuff and caustic negativism, I don’t imagine that would be too societally chaotic. I’d imagine lifespan differences wouldn’t become obvious until the 50s. So I could imagine some strife within families when your child is 50 and you are maybe 80 and it’s becoming obvious that your child will live longer and already has a higher QoL than you did at that age. Families already get a bit dysfunctional around wills and such at that age so that to me is the bigger concern or plausible source of tension. Like Boomer resentment multiplied, flipped, and personalized. Disease resistance as well (if it even works) is largely invisible on a personal level so I don’t think that figures too much.
More to my original point it could very well be that tons of the recipients get Alzheimer’s or some other hitherto unknown condition way earlier and stronger. Causing chaos, and something animal studies didn’t pick up. Our science is not optimized to detect that kind of stuff. And would we really be patient enough to wait for the original test tube generation to fully age before we implement it for others?
Oh yeah, there are always the fears about pushing straight to production with our children. But honestly I think that's the least of it with how dysfunctional all our institutions are these days. We'd be lucky if all that happened was everyone developed generative disorders by 60 instead of living to 120 when you consider how horribly we'd fuck it up even if the technology worked flawlessly.
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