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Small-Scale Question Sunday for December 14, 2025

Do you have a dumb question that you're kind of embarrassed to ask in the main thread? Is there something you're just not sure about?

This is your opportunity to ask questions. No question too simple or too silly.

Culture war topics are accepted, and proposals for a better intro post are appreciated.

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Anyone wanna share their peptides/supplements stack that actually does something? My current stack (aside from very basic stuff like Vitamin D):

  • Omega-3 for skin, inflammation, cognition - made a difference for my skin, not sure about anything else, make sure to get high quality one
  • Magnesium Glycinate for sleep - makes it easier to fall asleep, and helps with not feeling dead on wake up on nights when I don't get enough sleep
  • Selank: for anxiety, mood regulation, depression - genuinely makes me feel more happy and stable. I've been going through cycles of rumination, depression and mild panic attacks at night and they've pretty much stopped. I still get negative thoughts at night here and there, but instead of automatically falling into a negative feedback loop I can just observe the thought and move on. This is my first cycle of selank, so not sure how it's gonna go in the future but I'm very surprised to see such noticeable changes, usually with stuff like this changes are marginal.
  • Creatine: had to stop this one for now, but it's great for the gym. I've been reading research on 10gr dose providing visible cognitive benefits, so I will try that instead of 5gr to see if it makes a difference next time I can hop on it.

I get my omega-3 in the form of liquid fish oil. It's absorbed better that way. Tastes horrible though.

I also take D3 (large doses during winter every day, less during summer) and magnesium glycinate in the evening. Sometimes potassium citrate.

Vitamin K2 (trans-menaquinone-7) to make the D3 go where it should in the body.

B12 during periods of less animal product consumption.

I'm intrigued by this Selank thing. First time I've seen it. How did you hear about it?

B12 during periods of less animal product consumption.

I've tried it long time ago, unfortunately gave me really bad hormonal acne (went away after I stopped taking it)

I'm intrigued by this Selank thing. First time I've seen it. How did you hear about it?

It's been around for a long time, I've first read about it 10+ years ago when I was briefly interested in biohacking, but never got around to trying it. There's a 'chinese' peptide craze right now among techies and finance bros, I've finally decided to do a deep dive and try the one that I thought would benefit me most and it turned out pretty good so far.

Looks like Selank is a Russian invention though? If it's been around for that long, it should have been better known and regulated by now. I don't think I'll be able to buy it where I live, except as a 'research chemical'.

Yep, it is Russian and has been around since 1980s, but a lot of other peptides these days come from China and India. I'm assuming USA isn't interested in regulating stuff like that because it's so cheap so can't make much money off it. I also bought mine as 'research chemical' and had to mix it myself.

Hmm. Do you have to prove you're a researcher in any way?

Nope as far as I'm aware. I got mine off ebay, found a seller with lots of recent sales and went with it.