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PaperclipPerfector  4mo ago (text post)   2159 thread views

Wellness Wednesday for December 27, 2023

The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:

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New Swedish twin study just dropped[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274991/

Maybe exercising doesn't matter all that much?

Results

We identified four classes of long-term LTPA: sedentary, moderately active, active and highly active. Although biological ageing was accelerated in sedentary and highly active classes, after adjusting for other lifestyle-related factors, the associations mainly attenuated. Physically active classes had a maximum 7% lower risk of total mortality over the sedentary class, but this association was consistent only in the short term and could largely be accounted for by familial factors. LTPA exhibited less favourable associations when prevalent diseases were exclusion criteria rather than covariate.

Conclusion

Being active may reflect a healthy phenotype instead of causally reducing mortality.

I both want this to be true (because it would be a relief, in a way) but also don't (because it means your mortality isn't really modifiable by exercise). Any good analyses/critiques available?

  1. On Jun 5th 2023. So not that new.

One obvious confounder I just thought of: if a twin dies isn't the other twin going to feel, like, super bummed and like their life isn't worth living anymore?

According to ChatGPT4

Twins, particularly identical ones, often have a very close emotional and social bond. The loss of a twin can lead to significant emotional stress and grief, which might impact the surviving twin's health. This phenomenon is sometimes referred to as the "twinless twin syndrome," where the death of one twin can lead to deteriorating health in the other.

An alternate title for this study could perhaps be: Twinless twin syndrome kills more than good lifestyle habits protect

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