Grant_us_eyes
No bio...
User ID: 1156
Xcancel stopped working a few days ago due to them being sued by X, but I’ll try the alternate instances later. Or just give up and install the nitter extension. Thanks for the links.
Fair disclaimer; the links and exerts were from an effortpost I put together(but never posted), and when I went back later to double-check some information, found that the article was now behind a paywall. Of cource. I hate this fucking timeline.
So if you don't believe any of said exerts and call me a filthy fucking liar, the most I can do is shrug, cause I don't really blame you.
Solving cancer via LLMs and mRNA vaccines is already done and established science.
Kinda.
With 17 years of experience in machine learning and data analysis, Mr Conyngham is an AI pioneer – an electrical and computing engineer who co-founded Core Intelligence Technologies, and was a director for the Data Science and AI Association of Australia. Once UNSW handed him the genomic sequencing, for which he paid $3000, he got cracking to decipher the data.
The genomics team reached out to Pall Thordarson, director of the prestigious UNSW RNA Institute. A pioneer in nanomedicine, the Icelandic professor used Mr Conyngham’s data, crunched down to a half-page formula, to create a bespoke mRNA vaccine for Rosie. [...] What Professor Thordarson finds most remarkable is that a data engineer with no background in biology managed to generate the mRNA recipe.
Now, we all know about mRNA vaccines(cough cough Covid cough cough), and while their efficacy is... I'm sure, debatable and contentious. But in this specific instance, it at least had results;
“It’s definitely working,’’ Professor Allavena said. “When it happens that first time, it’s magical. Rosie’s cancer was really, really advanced but one tumour has shrunk quite a lot – probably halved. Even though it hasn’t completely disappeared, she’s so much more comfortable because the tumour was so big, and now the cancer’s shrunk away. Even the glossiness of her coat, she just looks a lot happier and healthier." [...] Rosie’s recovery has been a howling success, with most of her tumours appear to melt away in a matter of weeks. [...] Rosie’s devoted dog-dad is now working on a second vaccine targeted to attack one large tumour that did not respond to the initial treatment. The UNSW scientists started work on the genetic sequencing this week.
Again, not a magic cure-all or panacea, but sometimes you have to appreciate that the pig can dance at all.
However, turns out you don't need LLMs at all;
Sorry to be the downer because this is an impressive story in some senses. But it is ~trivially easy to make a single mRNA vaccine. It's not hard. I cure mice of various cancers with various therapeutics all the time. I've made mice lose more weight in a month than tirzepatide does in a year. What is hard and expensive is proving its BOTH safe AND effective in a randomized and controlled study in humans while ALSO manufacturing it at clinical scale and grade. I am happy for this man and his dog. It is impressive. But y'all are overhyping it.
(Emphasis both removed and added from the original.)
And, even better;
I literally have an ongoing cancer experiment where 100% of the untreated and control animals have had to be euthanized while 100% of the treatment animals are seemingly unaffected. But we're still extremely far away from "proving that it works." Science is hard.
(Emphasis added.)
Note: I am unable to check the twitter links for the above, as my account for twitter has been locked out barring cell phone verification, so I cannot confirm they work or link to what they say anymore.
I hate this fucking timeline.
So, mRNA cancer solutions are already a thing, but we can't have them, for reasons, I guess.
So the real question we should be asking isn't 'Can we do this', cause we already do. The question should be 'Do we trust Anthropic not to fuck things up' and I think I know what my answer is.
I typically abhor any kind of seltzer water, but I've found I have a very specific taste for Topo Chico's Lime and Mint. Very refreshing, no sugar/sweetener, zero calories.
Ah, skimmed over the review-bombing portion. A fair opinion.
I confess to being just a tad thin-skinned about the topic, as I've found people who bring up the entire 'GFL2 Chinese gatcha players' tend to run either toward casual bigotry and/or the kind of people whom would be making fun of nerds back in high school, with a strong whiff of grifting/tourism 'how do you do fellow gatcha players'.
Still, like I said. Understandable, coming from your PoV. Admittedly, I haven't played Reverse Collapse, mostly due to my first exposure being GFL and knowing how, uh... look, I know how these guys go in their writing. It's good stuff, don't get me wrong, but there's only so much existential depression I can take.
Another fact, apparently Chinese gacha players got angry that in GFL2 a female character has close relations with a male NPC character that they felt they were being NTRed because only the player should have any sort of relationship with their gacha waifus so they review bombed Reverse Collapse instead. Chinese gacha players seem to be a different breed entirely.
It's a bit more involved that this; the character in question was from GFL1 and represented the QBZ-14 rifle - which, for those not in the know, is the national rifle of the Chinese army, so there's a bit of national pride involved there. Second, when the company that owns GFL took a look at the matter, resulted in an official statement involving potential corporate sabotage, atleast one fired(female) writer, and a flood of original writers coming back from working on thier side-project Project Neural Cloud and noting a marked increase in writing quality from the early game in GFL2 to the current.
So there's a bit more teeth there than just 'blooh blooh chinese weebs are weird fucks'.
Dandyism has entered the chat.
I have weird obsessions, okay? I only wish I had gotten that book when it was new, as opposed to now. That price tag, yikes...
Very true. I’m just trying to point out that, while I one among many with issues regarding Darwin, I don’t recall him ever using Llms to try and back up his arguments.
I... I'm sorry. What? I cannot even begin to fathom how someone could come to this conclusion.
I'm not being disingenuous, or anything like that. If you have any articles and/or references to point me at, I'd love to read them.
? This is a common rhetoric that's often seen on twitter. As much as I hate defending Darwin, he kinda ghosted before referencing LLMs as some arbiter of reality became very popular.
Using LLMs for artwork is a very interesting case of economic forces in action.
Turns out, it's entirely possible that alot of artists are simply pricing thier results too high and are getting bit because of it.
Really hard to beat The Devil's Spear. That sheild drop moment is just utter perfection.
Quite. Naming your system after a fantasy tool that was once used for good and has been corrupted by evil and thus dangerous to use with skeptical returns should have everyone giving you a side-eye and going 'Bruh'.
Do you have any idea how difficult it is nowadays to track down the actual Code Noirs in regards to treatment of slaves in the American South?
To quote;
VI. We forbid our white subjects, of both sexes, to marry with the blacks, under the penalty of being fined and subjected to some other arbitrary punishment. We forbid all curates, priests, or missionaries of our secular or regular clergy, and even our chaplains in our navy to sanction such marriages. We also forbid all our white subjects, and even the manumitted or free-born blacks, to live in a state of concubinage with blacks. Should there be any issue from this kind of intercourse, it is our will that the person so offending, and the master of the slave, should pay each a fine of three hundred livres. Should said issue be the result of the concubinage of the master with his slave, said master shall not only pay the fine, but be deprived of the slave and of the children, who shall be adjudged to the hospital of the locality, and said slaves shall be forever incapable of being set free. But should this illicit intercourse have existed between a free black and his slave, when said free black had no legitimate wife, and should said black marry said slave according to the forms prescribed by the church, said slave shall be thereby set free, and the children shall also become free and legitimate ; and in such a case, there shall be no application of the penalties mentioned in the present article.
Now, there is a valid arguement to be made that the enforcement of said laws wasn't exactly strict, or that there wasn't fair and equatible treatment thereof. But you can't say that, by the written law on paper, that the situation was a case of 'It's free real estate!' for people to do whatever they want with thier female slaves.
And, yes, this is only one case of a very specific state in regards to thier treatment on slaves. But it was also put to paper in 1724. I don't have the time to invest to track down and compare all Code Noirs from that particular time period, or do a comparative analysis on how things changed over time leading up to the Civil War.
If you strech the time period back to 1930, you could make an argument that 1930 to 1990s represents a solid degradation on gun rights, from the twisted origins of the NFA Tax Stamp in 1934, the Gun Control act of 1968, the fucking Hughes Amendment, and culminating in the assault weapons ban in the 1990s.
I've been a little bit at a loss as what to sink my teeth into as of late, so I've mostly been playing a slightly-modded run of The Long Dark to work on getting my 500-day acheivement.
If anyone has the urge to play a survival walking game, I do endorse it, even if I think Hinterland has been a little shizoprenic in terms of how they've been developing the sandbox side of things as of late.
I'm a little skeptical of this, mostly because I've never seen it in action.
I have, however, much to my shock, seen examples where women in a pre-established group reacted in a surprisingly vitriolic manner to someone who's much more attractive suddenly popping up out of nowhere.
College nowadays is just a mechanism to take advantage of tribal nepotism and entry into higher strata of social circles and connections.
Sadly, I learned that one far too late.
Personal theory: AOC (or her handlers have her) dresses down deliberately to make her look worse than she actually is, because alot of women tend to disfavor women that look better than they do.
Zendaya is still ugly, though.
Battletech was my first introduction to table-top wargaming. I remember playing with it as a kid, with the battlemech setup sheets that, uh, were just a little bit litigatious.
Years later, when I finally get a bee in my bonnet and start looking into painting miniatures, I decide to cut my teeth by purchasing a box of Mechwarriors and start looking into see what's been happening with the IP lately...
...only to find that it's decided to go a similar route as Warhammer 40K and go woke and gay.
For fuck's sake. By this point having anything you love become widespread and popular is a curse rather than a blessing.
Counterpoint; Is this because they enjoy old things or just that everything new nowadays sucks?
It's one of the refrains I've seen in the video game arenas I frequent; 'Why would I be giving money to people who hate me when I can just keep playing older games?'
If I can crack open a twenty two year old game(holy shit) and get what I feel is a better Star Wars experience than anything that's come out since then, is it because I like old things or that everything nowadays that is bad?
Even worse, while it seems to be very easy to run across good video games nowadays in the indie market, given how much exposure they get, finding good books that are very male-coded is quite difficult. I can think of atleast two recent authors off the top of my head that are very male coded(KD Robertson and E William Brown) and while not exactly high-brow, they're still fun, good reads.
I want to argue otherwise, but then I remember the entire book-shredding subplot and the prevalence of black box engineering and just throw my hands up in defeat.
I guess we're in the Eclipse Phase timeline, then.
Better than Pantheon, I suppose.
Now that I point out that this is an obvious strawman
Sigh.
If it was so easy to point out how LLM benefits the common man, then you'd have an easy response in your back pocket. You didn't, and instead responded with ridicule, the equivalent of 'lolno'.
I'm not accusing you of bad faith. If anything, the only hostility in this argument I'm seeing comes from you. I'm asking you to back up your argument with something. I've seen instances of LLMs being utilized to impressive degree, and I know of atleast one person that I find interesting to follow who says similar, so while I'm skeptical I'm atleast willing to hear him out.
My basic argument boils down to this: I don't think you can extrapolate the above and expect similar return out of the common man, or ways it benefits them.
Still, I do want to step back and clarify something. When I see the argument in the wilds - I'm not talking about the motte, I'm talking elsewhere about people comparing Data Centers to Nuclear Power, I read their implied statement as to say that, yes, they equate Data Centers in importance to Nuclear Power. And when asked 'why', they never give a solild answer - they either reflect, or attack. Or, as you called them, my strawmen arguments. It's why I brought it up. I find the comparison rather silly, or an actual use of a slippery slope fallacy.
- Prev
- Next

Not just the PR space; People have been pointing out as of late that with the shift in NFA registration/tax stamp, the most recent wins in the courts, and the ATF more or less stating outright they're not going to argue the point, people are now capable of doing things free and clear that would have had the Federal Government gleefully murdering your wife and kids and celebrating about it afterwards.
Granted, that line of logic leads to places alot of people don't want to go. Conversely, given how the Days of Rage worked out for the left, well...
More options
Context Copy link