The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:
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Requests for advice and / or encouragement. On basically any topic and for any scale of problem.
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Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.
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Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.
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Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).
Jump in the discussion.
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Semaglutide Trip Report (Real, Factual, as seen on Erowid):
Recently, due to a change in meds and an increasingly sedentary lifestyle, I'd packed on more pounds than I cared for. I'd bought a weighing scale but forgot to buy batteries, so it was only on my return to India that I found out I'd gained 5 kilos that I didn't need.
I'd convinced my mother to start oral semaglutide a while back. She desperately needed it, being very obese to the point that fatty liver was headed straight for cirrhosis. Not to mention she was diabetic, so it was a double whammy. After some difficulties with initial GI upset and nausea, she was happy enough on it, and probably lost about 5 kilos. Still plenty to go, so I keep hounding her to see her endocrinologist and up the dose.
I was already a semaglutide fan from early clinical trial days, so I had few qualms in ordering some for myself. By Indian standards, quite expensive, around 100 USD for a month's supply of 7mg tablets. By Western, or even UK standards? A pittance. I could afford that without any concern.
Normally, you're supposed to start at ~3mg OD for a month and then titrate up, but I was impatient and willing to take the risk of a higher dose. The degree of weight loss is quite dose dependent. I opted for 7mg, ordered several months worth to go, and went right at it.
It's been 4 days, but the effects were noticeable from day one. It absolutely slashed my appetite, I normally skip breakfast, and usually have 1-2 large meals a day, but whereas I normally get peckish past noon, I got to 6pm before getting hungry and realizing I hadn't had anything to eat.
I'd been out with friends and grabbed pancakes dripping with chocolate, and only managed to have half my plate before I had to give up. Later in the day, I can just about have one meal and consider myself full. I've had to force myself to eat more as I've been working out quite hard and wanted to see gains.
No side effects to speak of. My stomach is as it's always been, and the plumbing hasn't given out. I've been emboldened to order another 3 months of it, just to tide me over while I'm back in Scotland.
TLDR: Fucking amazing. I could drop my caloric intake to about half without being desperately hungry, and to about 70% while feeling entirely normal. I'd be willing to pay a much higher price for it if I absolutely had to.
My view of GLP-1s has a similar flavor.
me at 35: LSD is so consciousness altering! whoa!
me at 45: GLP-1s are so consciousness altering! whoa!
What I was expecting was a reduction in hunger, that makes sense. What I find really interesting is when I do have cravings, or feel hungry, the "seeking" behind what I do about it is gone. I feel a lot more activation energy is needed to pit stop at the bakery, or get a goodie out of the pantry, or even scoop myself up another helping.
I think this is the dopamine system being suppressed. But... only at the extremes?
I haven't become an adhedonic robot though. Sex is still excellent and when I do order something delicious and eat it I still enjoy it.
How does this make any sense?
Ozempic would be "too good to be true", but thankfully the universe is apathetic and cold, and doesn't work that way. God knows that an enormous amount of effort has been put into finding some massive downside, to little avail.
I wouldn't call what I've experienced consciousness altering, at least if you don't think taking a Tylenol to reduce pain makes it a psychotropic drug haha. But it does make me less hungry. I'm like 50% sure it's also decreased my craving for liquor, not that I drank that much in the first place.
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