Do you have a dumb question that you're kind of embarrassed to ask in the main thread? Is there something you're just not sure about?
This is your opportunity to ask questions. No question too simple or too silly.
Culture war topics are accepted, and proposals for a better intro post are appreciated.
Jump in the discussion.
No email address required.
Notes -
What exactly causes male fertility to decline with age and how closely related is it to increased mutational load? How many more mutations do the children of old fathers have?
I haven't studied the gerontology of spermatogenesis but IIRC you loose ~16% of your testosterone secretion per decade.
Something similar must apply to your
luteinizing hormone I guess.
It's likely antioxidants reduce spermatogenesis loss, I believe I had read studies about that a long time ago.
Spermatogenesis should mostly be a solved problem, IIRC Ashwaganda +100%> ?
HCG, etc
But indeed the real problem is the dna degradation of your sperm.
There was a paper on hackernews this week, about increased epigenetic heritage loss for aged males.
Despite my erudition in gerontology I have never been able to find a compelling answer as to why life on earth works.
As we live we accumulate mutations, 60000 per day. Yes our sperm is much more protected than the rest but even if sperm age slower than the rest, it still age. And therefore that Ageing should be passed and herited to the offspring.
Therefore by generation to generation we should dramatically accumulate buggy mutations.
And yet, mysteriously, we don't.
How is this possible and how isn't this technology the way to achieve cellular and therefore eventually possibly whole body Immortality?
More options
Context Copy link
More options
Context Copy link