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Wellness Wednesday for May 24, 2023

The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:

  • Requests for advice and / or encouragement. On basically any topic and for any scale of problem.

  • Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.

  • Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.

  • Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).

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I'll keep this short and sweet. I'm very tempted to try and hop on the semaglutide train. It seems like folks here have had decent results. I have a few hesitations:

  • First, morally, I feel like I should be able to lose weight myself. With enough physical activity (playing soccer etc) I at one point was able to have an incredible body with awful eating habits. I've improved my eating habits dramatically but I know for sure that I still have unhealthy tendencies. I should be eating less and differently. I can cycle an imperial century and it's almost trivial, but actual weight loss has remained elusive.

  • Second, I feel like this gold rush will end in tears a la COVID vax. I'm ashamed I hopped on that train so early though I didn't have any side effects and rarely encounter any through medication anyway. What are the chances this all ends up being a huge mistake and I shave 5 years off of my life in exchange for losing a beer belly?

I'm also tempted sometimes, but at the same time, if semaglutide only helps you be less hungry, I don't see the point for using it on myself. I'm pretty capable of simply denying my urges (for 6 out of 7 days, anyway) and avoiding eating much that way. Unless semaglutide also helps your metabolism or has effects other than making you less hungry, then I don't think I need it, I can just mostly do it on my own.

I've had the same "I can do it myself" mentality for years, and I did have intermittent successes before starting semaglutide. I can stick to a diet perfectly for roughly a month at a time and lose 10 lbs, the problem always comes when life gets stressful and suddenly my mental energy assigned to the diet starts to decline, if It's crunch time and I have an important presentation tomorrow, I can't also be really fucking hungry because I'm in a 1000cal/day deficit, I'll just throw the diet out the window for the stressful time period.

Semaglutide takes care of all that, and I don't need to have zero stress in order for me to stick to the diet, that now happens more or less effortlessly. I still need to have enough mental space to prep my diet foods at regular intervals so I don't eat out instead of eating my home-cooked stuff, but that's a much lower bar than tolerating hunger.

Can it be taken intermittently? Like, in your example scenario, can a person just live normally for roughly a month, but then take it for a week when life gets stressful... then cycle back off it?

The recommended dosing has you slowly ramp up the dose over like 2 months until you get to the truly effective amounts. I suspect that you would get very large gastro-intestinal side-effects if you just went from 0 to the effective dose. Semaglutide also has a very long half-life of a week, so if you're injecting 1.0mg/week steadily, to get the same blood concentration with a single injection you'd need 2.0mg. I think it would be a fairly bad idea, there's a good chance that the diarrhea and vomiting you'd get would wipe out any mental benefits from the lack of hunger.