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self_made_human  Grippy socks, grippy box  1mo ago (open.substack.com)   1589 thread views

Escaping the Jungles of Norwood: A Rationalist’s Guide to Male Pattern Baldness

open.substack.com

Out of enlightened self-interest, I did a deep dive into the topic of male pattern baldness, and after freshening up on my rather rusty Bayes', I decided that I'd gone to enough effort to justify a proper blog post. Here you go.

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...you didn't hear there's some new molecule that apparently revives dormant hair roots and in tests, bald men grew their hair back?

It's nothing hormonal and doesn't have the dire risk profile of finasteride etc.

I would find that quite interesting if true - both because I'm in the affected demographic, and because I consider MPB as one of the main pending milestone cases for radical medical life extension. In many ways it's an ideal baby version of the problem: age-related, highly prevalent, great market potential, no stigma around research, external, easily measurable objective success metric with quick feedback, doesn't directly involve any critical organs. It's quite likely that age-related organ failure involves a lot of metaphorical "hair", so as long as we couldn't figure out how to stop and reverse age degrading actual hair, I figure there is no chance that we could do this to the "hair" that might be some ion channels on the pancreas that we only have a tentative understanding of.

Nope, must have missed me. Got a link handy?

Okay, it might be noting, but here's some keywords you can look up.

https://x.com/hairypapasmurf/status/1935048213842772035

I mean, is this a peptide? Do you have a name?

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