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Culture War Roundup for the week of March 23, 2026

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What about cryonics? What's new? Where else would I read new cryonics if not a pitch on LessWrong?

"Traditional" cryonics requires a crisis response to a customer's death. A person dies, people are alerted, and a plan is carried out to evacuate a body to administer cryogoo-- glycerol. That body is transferred to cold storage and suspended in liquid nitrogen with a barrier of one fancy cask. The liquid nitrogen creates extreme temperatures for preservation, around -192C, a temperature that comes with risks-- human tissue kept at -192C tends to be very fragile. Another pressing issue is that the goo filling-to-freezer process takes time, and bodies stop all kinds of maintenance after death. Dying with imperfect preservation means if someone did find a way to upload your brain to the Matrix, or reanimate your corpse, unless they've fully cracked the mysteries of regenerative medicine the experience may not be to your liking.

Why is this this culture war? Nectome's new method offers a workaround to the last problem: kill yourself.

The result is a protocol that my company, Nectome, has spent the past ten years developing. After years of experiments in the lab and in the field, learning about the complexity of end-of-life biology, and after refining our protocol to make it robust and repeatable for real people in real-world clinical settings, we are now ready. We've developed a whole-body, whole-brain, human end-of-life preservation protocol based on neuroscience first principles. We are capable of preserving every synapse and almost every protein, lipid, and nucleic acid throughout the whole body. Brains are connectomically traceable after preservation[1]. Our preservation is so comprehensive that current neuroscience theories imply it preserves all relevant information necessary for future restoration of a preserved person.

Nectome wants you to have the option to end your life so they can preserve your bits, bobs, and neuronal structure, increasing the chance you emerge intact down the line. You can read a slightly more detailed overview in this PDF from Nectome with citations. You can compare it to the big brand-name cryonics company in the US named Alcor. Alcor has facilities located in Arizona, which is a state with cheap land, no hurricanes, low humidity, and a favorable regulatory environment. Good things for long term groundskeeping. Unlike Alcor, Nectome plans to set up shop in Oregon. Also unlike Alcor, Nectome clarifies they will host no brains in jars with holistic, rather than trope filled, process.

We preserve the whole body, including the brain, at nanoscale, subsynaptic detail. We are capable of preserving every neuron and every synapse in the brain, and almost every protein, lipid, and nucleic acid within each cell and throughout the entire body is held in place by molecular crosslinks.

The business pitch relies on the fact that Oregon has MAID, colloquially known as assisted suicide. Rather than keep cells frozen in place with extremely low temperatures, Nectome's goo formula does more work to stabilize structures chemically, which allows a moderate preservation temperature at -32C. This process must be completed immediately following death. So if a client can plan around, or potentially induce, a state recognized terminal illness, they can purchase a flight to the state of Oregon, end their life, and receive the latest greatest chance at... something in the future. Don't want to miss the singularity or omnipotent medicine? No cryonics company promises anything like that, they usually only agree to look after your frozen bits for as long as is feasible.

About that, Nectome's founder is also involved with Eon Systems, a company currently working on brain emulators. They generated a viral story with apparent progress on a fly connectome earlier this month. Specific claims of hype are contested, but progress on mapping, building, and simulating brains seems real. Much has been written on MAID slippery slopes, but it seems we already have a current legal avenue to test a "freeze me" future with an upload waiting room. Take the upload to Elon Musk's Afterlife, which is a RuneScape clone by the way, replete with a procedurally generated non-stop feed of his greatest twitter hits at your finger tips into eternity, or until transcendent beings awaken you.

With so many sci-fi fantasies filling up the horizon, why not kill yourself and wait awhile? What did you think transhumanism meant, anyway? vibes? papers? essays?

Is he Elizabeth Holmes long lost brother? Same vibe.

Anyway couple of thoughts - yes killing yourself will make any kind of preservation easier. They could even start the process before you are dead. That is not a big break trough.

Anyway - there are a lot of lab mice in the world. If the technology was real - they could show something with a lab mice after it is preserved.

I think a lot of cryogenics relies on the idea that in a couple hundred years our technology will be so advanced that they will be able to bring people back from the cryogenic state. Therefore, they do not need to prove that we can bring a mouse back right now, with our current technology.

I think it's all crazy to assume we'll keep progressing the way we did in the last century and a half. We're going to go into a population crunch soon. We'll recover from it, but who knows what will happen to the cryogenic-ally frozen in the meantime?

I think it's all crazy to assume we'll keep progressing the way we did in the last century and a half

Most cryonics believers aren't really assuming that, just that we'll hit some kind of A.I. singularity soonish that'll have the same results.

That is a recent development. When I first learned about cryonics, I didn't expect AGI to be nearly as imminent or realistic as a possibility.