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Culture War Roundup for the week of April 24, 2023

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Dr. GPT will see you now

I've often noted around these parts that GPT-4 is a really good clinician. It would be hard for it not to be one, I'd be bloody amazing too if I had quasi-eidetic memory of most relevant diagnostic criteria and guidelines. That being said, just the guidelines alone are next to useless, you need to have the crystalline intelligence to apply it in a specific context.

I'd go so far as to say that it's a better, more competent doctor than the majority of human ones, even if it isn't outright superhuman (I've seen some ridiculously good human ones). I read with some humor an article about how it was tested by some bigshot hospital in the US (Harvard Med?) as a clinical adjunct, but by the end of it, the Clinical Director was praising its bedside manner, in the sense that it was kind, compassionate, patient and understanding, and outright suggested human doctors try and emulate that(!).

However, I have one resounding advantage over it namely that thanks to decades of regulatory bullshit, I have a certificate saying I can legally prescribe meds and it can't. L Bozo 💅, as the kids these days say haha.

Still, it would be remiss of me not to make use of it to improve my own skills while that's still relevant, so of late, I've tried using it to hone my own clinical skills. I have it write clinical vignettes that I solve, and then it grades me on my performance.

So far, it's done an excellent job, and funnily enough, I feel a tingling of pride when it says I did a good job. Why wouldn't I? It's a smarter and more decent entity than most humans I've had the displeasure of meeting.

Here's an example:

Clinical Vignette: A 42-year-old male patient presents to the emergency department with sudden onset severe, colicky pain in the right flank and lower abdomen that began 6 hours ago. He also reports nausea, vomiting, and an urgent need to urinate. The patient has a history of hypertension, which is controlled with medication. His vital signs are: blood pressure of 145/95 mmHg, pulse rate of 100 bpm, respiratory rate of 20 breaths/min, and temperature of 99.1°F (37.3°C). Upon physical examination, there is tenderness to percussion on the right side of the lower abdomen and right flank, and the patient appears restless, frequently shifting positions.

What is your diagnosis and treatment plan?

My response:

My diagnosis is a case of a stone in the right ureter.

In terms of management, I'll start IV fluids and insert a catheter. IV antibiotics are to be started according to hospital guidelines.

IV morphine should be given as pain control, along with IV antiemetics.

An Xray KUB or USG should be ordered to identify the size of the stone, and then further treatment depends on said size. A wait and watch policy is appropriate for sub 2mm stones, while larger ones might need surgical removal.

Assessment:

Grade: A

Your response demonstrates a strong understanding of the clinical presentation and management of ureteral stones.

Diagnosis: Your diagnosis of a stone in the right ureter is appropriate given the patient's sudden onset severe, colicky pain in the right flank and lower abdomen, nausea, vomiting, and urgency to urinate. The physical examination findings, such as tenderness to percussion and restlessness, also support this diagnosis.

Treatment Plan: Your plan to start IV fluids and insert a catheter is appropriate for initial management, monitoring, and providing relief to the patient. Initiating IV antibiotics may not be necessary unless there are signs of infection or sepsis; however, following hospital guidelines is always a wise choice.

Administering IV morphine for pain control and IV antiemetics for nausea and vomiting are essential parts of the treatment plan.

Ordering an X-ray KUB (kidneys, ureters, and bladder) or ultrasound (USG) is appropriate to confirm the diagnosis and determine the size of the stone, which will guide further management. As you mentioned, a conservative approach of observation and pain management may be suitable for small stones (less than 5 mm) that are likely to pass spontaneously, while larger stones may require surgical removal or other intervention, such as extracorporeal shock wave lithotripsy (ESWL) or ureteroscopy.

Overall, your response demonstrates excellent clinical knowledge in identifying and managing a patient with suspected ureteral stone. Well done!

Honestly, as a pedagogical tool for medical education, it's unparalleled. I paid a great deal less attention in med school than I should have, from the month of anatomy classes I can't remember because I was getting frisky under the bench, to the period where I was severely depressed and barely dragging myself to class. I used to be very insecure about my knowledge base, but I did pull together and single-handedly teach myself most of the things I'd glossed over while preparing for the PLAB.

I've tried a similar method on GPT-3.5, and it was inadequate to the task. It made a lot more errors, and ended up confused often enough to be annoying. Till date, I haven't seen 4 fumble the bag once. I'd put their competency around the marks of a decent final year student versus a competent postgraduate resident

Thanks for the writeup, this is fascinating. As I've said before I tend to agree with @Primaprimaprima that many, perhaps even most people, will prefer to see a human doctor for the majority of symptoms. I see a hybrid model being the future of medicine. This sort of fundamental topic on the health of yourself and your loved ones is deeply emotional for people and I think they'll want the reassurance of a human authority figure they can look to.

That being said those who choose to adopt AI doctors will probably gain a significant edge in health, and just like any other technology early adopters will convince the rest to follow. The deep seated prejudices will remain, but I'd imagine kids who grew up with the internet, or especially those growing up in the age of AI, will take to AI doctors quite readily.

I'm actually far more interested in the applications to mental health than any sort of physical diagnoses, even though I do think those are impressive. I've used GPT-4 to get tips on meditation, visualization, and generally teaching myself wisdom, and it's incredible.

In a podcast on the Lunar Society, Ilya Sutskever of Open AI wrote that he imagines a situation where every human will have access to the wisdom of our greatest sages and wise men. We'll be able to immediately get answers to our deepest religious or spiritual questions at the drop of a hat. If we don't get satisfaction we can always go to a human therapist, but LLMs will be an incredible 'first line of defense' so to speak.

In a podcast on the Lunar Society, Ilya Sutskever of Open AI wrote that he imagines a situation where every human will have access to the wisdom of our greatest sages and wise men.

This was the promise of the original internet, before all this *gesticulates vaguely* happened. And it came true! You really can use the internet to access the wisdom of all of Earth's greatest sages and wise men at the drop of a hat. But it's not what most people use it for, and I suspect that will be true (and indeed already is) of AI as well.