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A blow to the CICO theory of obesity: Pre-fertilization-origin preservation of brown fat-mediated energy expenditure in humans
I find this noteworthy for three reasons —
There’s possibly an easy and natural intervention for obesity. The Japanese neurotically dress for the weather, so how great will the effect be for those who accept the cold? “College woman walking to a party in winter wearing a short dress” was a joke when I went to school, but it was apparently pro-natal. Is it the fluctuation which is most significant? Does it need to be tied with the day-night cycle?
This is more evidence that humans are shockingly attuned to specific conditions they evolved in, which should be reverse-engineered to find more potentatial interventions for human flourishing. We are much more animal than we like to admit.
How many other “willpower problems” have less to do with willpower and more to do with 2nd and 3rd order effects which are hidden from us, or which compound invisibly? There are probably many more for obesity alone.
A) CICO necessarily follows from the Second Law of Thermodynamics, which is perhaps the most confirmed scientific theory of all time. The day you disprove it is the day physics gets really, really weird and reality as we know it ceases to make sense. So CICO is a theory in the sense that conservation of energy is a theory, which is to say it is as cold and hard of an absolute as we know to exist in the universe, no amount of obesity cheerleading will change that.
B) The effects noted in the study are frankly not that big. Like a 3% increased likelihood of active brown adipose tissue, which might increase total energy expenditure of the bodies resting metabolism of up to 5%. So conceiving in the winter gives your baby a slightly higher chance of being slightly better at burning energy, which is only a benefit if you live in a post-scarsity world.
"You eat too much and you dont exercise enough" remains the core of any and all successful diet criticism.
The naive version of CICO compares your meal plan to your gym time. The normal version compares all the food (including drinks!) you consume vs. all your planned or incidental physical activity. The true version compares the bioavailability of all the nutrients you consume vs. all of your metabolic activity, whether that's moving your muscles, thinking, growth, healing, generating heat, or anything else.
I have yet to see any diet plan that uses the true model of CICO. The closest I've seen is a single number for "base metabolism" that you back-calculate from your weight trends.
I think you're pushing a strawman, but I'm open to seeing a diet plan that uses the "true CICO" model I described. Anything less precise can't follow from raw thermodynamics.
You don't need official diets for CICO it's self evident. Reduce food consumption and/or increase activity until you lose weight. Still haven't lost weight? Decrease/increase.
Problems:
People tend to lack self control. If you had self control you wouldn't be fat.
People tend to over-weight the activity part. So really just forget about CO and reduce CI until you start to lose weight. See problem one.
Expand to why you're poor and struggle with addiction.
"you're poor because you don't earn enough" A lot of dieting advice is similarly circular or unhelpful. Thankfully we now have GLP-1 drugs, which seem to work for many people
There's a big distinction between obesity and poverty:
To become not-poor, you need to both do things you are currently not doing and do them in a way that gets other people to give you money for those things you do. You're adding behaviors, and you have to socially coordinate.
To become not-fat, you only need to not do a thing (eat). It requires no social coordination whatsoever, it requires no additional action, you literally only have to choose to not pick up the fork.
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Be careful with that poison, I'm reading some horror stories about people going blind on that shit. And the media is staying as silent as possible for that one.
I suspect this is due to comorbidities like diabetes, in which blindness is a risk factor
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No, you're poor because you don't do relatively simple things. And yes, hopefully GLP-1s help a ton.
the SS was written a long time ago when a HS degree was good enough. now you need college
So it's down from 97% to what?
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