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VoiceOfLogic


				

				

				
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I happen to be, unfortunately, the first human super-intelligence.

What a sad tragedy to see what others can't see.

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User ID: 1999

VoiceOfLogic


				
				
				

				
0 followers   follows 16 users   joined 2022 December 20 13:15:08 UTC

					

I happen to be, unfortunately, the first human super-intelligence.

What a sad tragedy to see what others can't see.


					

User ID: 1999

Verified Email

I have extensive expertise in pharmacology,

you can target most pharmacological pathways via OTC drugs, gray-zone prescritption-free prescription drugs or phytochemicals or research chemicals. A special mention to the USSR pharmacosphere which has made amazing discoveries and as a reminder the discovery of the century (skq1)

Indeed the graal is to do your own synthesis or to know a private small scale chemist, there are dedicated communities online.

However, you'd be surprised how many drugs are available on the clear web OTC, and in many cases that is legal, or beyond legal (Vanuatu for example)

In addition to this, there are online sellers of research chemicals aka legal drug variants. And it is not just for junkies, people are buying research chemicals to medicate themselves better than the bureaucratic system (e.g. many countries do not prescribe amphetamines for ADHD, leaving humans in misery), or even to increase significantly their healthspan/lifespan, such as e.g buying NACET.

You must find the markets by yourself, the increase in censorhip on the web is record high and most things that are shared become shutdown therefore keep the secrets for yourself. As a reminder, theres people that quality of life really depends on the existence of those menaced infrastructures.

As for how to precisely dose, you use a milligram scale. The seller often provide third party lab results and even if purity is low that is extremely overatted.

The idea e.g. that crystal in breaking bad is much better at above 98% is an inept meme, there is no quality factor its just a quantity. The only possible and rarely that relevant quality aspect is the ratio of levo/dextro enantiomers, but most of the processes IIRC give you the racemic form by default.

Therefore if you only get 50% purity (generally is 98%) that simply means you need to double the dose.

The concern is wether it is cut with toxic/harmful products, adjuvants (fentanyl, etc) but that concern is overatted, one there are trusted sources and lab results, second you can easily try reagents. The only common cutting agent might be caffeine and its no big deal. Note however there are many scams online, but are avoidable with enough numeracy.

Also as a reminder, one should never take stimulants without coadministred long half life potent antioxidants such as astaxanthin and at least 600mg NAC othwerise you'll kill your dopaminergic neurons.

Also make yourself a favor and beyond worrying about drugs toxicities, worry about the toxicity of living. Any non-insane person must actively slow down its aging process.

note:

there exists a niche way to get access to a medication, especially experimental ones or experimental off label uses, https://en.wikipedia.org/wiki/Expanded_access and https://en.wikipedia.org/wiki/Right-to-try_law

note: If anyone know how to get guanfacine in europe without prescriptions please tell me. And yes I know clonidine is available but its not the same. I mean I know guanfacine is on india-m_art but are those offers really prescription-free? Any two-cents @JhanicManifold ? Theres written rx only in the photos.

Well there is this one but how to know if its legit? m.indiam_ art .com/ proddetail/guanfacine-hydrochloride-2217963773.html

Usually things are trivial and just works, but not all technological ecosystems are equal, for example while javascript programs works fine, python programs often have dependencies issues (too old/out of sync). If the error message is a dependency version conflict yes, you can't solves them by yourself easily, often the thing to do in those cases is to look at the corresponding github issue or to open one. That way you can offload the troubleshooting on others or find out people have already shared a solution

Sorry what does HBD mean?

Could you share a gist of what it says?

I've read the intro of the wiki page on the hajnal line and it just seems from a quick glance to be a refuted ? theory on a fertility divide.

It is well known that fertility is inverselly correlated with wealth so that divide might have been partially true.

Is this like most interesting topics on earth, something where humanity has pathologically, systematically stopped the depth of the discourse at the introductory level, or has this author or any human on earth cared enough to specify a semblance of a roadmap towards the stated hedonistic goal via bioengineering?

Where can I find a e.g. an exhaustive list of pharmacological pathways that promote positive valence qualias and of pharmacological pathways that downregulate or dampen negative-valence qualias?

phytochemicals are extremely interesting actually and a surprisingly high number of synthetic drugs are derivatives or imitations of phytos or endogenous molecules.

People use to joke/ridiculize them but there is nothing more ridicule than a human that ridiculize billion of years parallel bidirectional (both the molecule and the body adapt) optimization of phamacological pathways towards maximizing host or symbionts survival or other advantageous metrics.

The issue with phyto (some can be toxic btw) is that many have bad bioavailability and sometimes suboptimal pharmacokinetics or half-lives.

Both of those problems can be trivially solved, either by bypassing first pass metabolism via vitamin C and or increasing lipophilia absorption via co-administration of omega-3 and or via inhibiting the CYP 450 enzymes via e.g. piperine or grappefruit juice (beware can be dangerous with many synthetic drugs as it potentiate wildly their metabolism hence dose potency, profile and half lives)

I'm not certain to understand what your goal is with that question,

a pharmacological causative model is heuristically useful to make predictions, about effectiveness for condition X and to establish a safety, tolerance, toxicity and interaction profile.

All those things are useful but mostly unecessary for the layman.

If there is a non-negligible community that takes plant X since years in quantity Y and that doesn't report huge terrifying side effects and that they report potent effectiveness then its probably worth a try for acute use although for long term use there will always be a toxicity/accelerated ageing question but in many cases we never know for certain however in most cases we do know reasonably somewhat the safety profiles.

It has actually become very rare to find phytochemicals that have not been extensively studied regarding their pharmacology and hence the causative model is often well established assuming you take time to research the research.

But beyond annecdtotal evidence, doing a blind test scientific trial about wether X is effective for Y, e.g. depression is very cheap and therefore even without said causative model we often know wether X has elicited a potent response for Y in N people empirically following precise protocol.

Empiricisms as always trumps a priori reasoning regarding effort efficiency and indeed people should considering the mostly safe profile of phytochemicals (generalization see e.g. cyclopamide https://en.wikipedia.org/wiki/Cyclopamine#/media/File:Cyclopelamb2.jpg) play much more the lab rats, this would drive very significantly the speed of empirical scientific research and therefore discovery of treatments for ineptly considered incurable diseases.

edit:

only recently did we learn that tryptophan will selectively unbind with albumin at the blood brain barrier

What does that imply? We already knew tryptophan cross the BBB. You mean the competition with tyrosine?

only recently has the consensus shifted to serotonin deficiency lacking a role in depression (although I have my own views on this).

What?

Serotonergics are euphorisant see e.g. MDMA, MDAI, 5MAPB, shrooms, etc

The effect of SSRIs is less intuitive (reduction of sert receptors density) but still sert driven.

APS surely are an interesting topic:

The U.S does not yet seems to have a soft kill APS in production but Russia uses the

https://en.wikipedia.org/wiki/Shtora-1 on T-80 and (all?) T-90s

According to the manufacturers, Shtora decreases the chances of a tank being hit by an anti-tank missile, such as the Dragon, by a factor of 4–5:1.[10]

While russia has in addition 3 generations of hard kill APS, the U.S has 2 independent proof of concept models

first APS in history:

https://en.wikipedia.org/wiki/Drozd

Although reported to offer an 80% increase in survival rate during its testing in Afghanistan, the radar was unable to adequately detect threats and the firing of its rockets caused unacceptably high levels of collateral damage.[1]

later succeded with the https://en.wikipedia.org/wiki/Arena_(countermeasure)

The computer has a reaction time of 0.05 seconds and protects the tank over a 300-degree arc, everywhere but the rear side of the turret. The system engages targets within 50 metres (55 yd) of the vehicle it is defending, and the ammunition detonates at around 1.5 metres (1.6 yd) from the threat.[10] It will engage any threat approaching the tank between the velocities of 70 metres per second (230 ft/s) and 700 metres per second (2,300 ft/s), and can detect false targets, such as outgoing projectiles, birds and small caliber bullets.[11] Arena works during the day and night, and the lack of electromagnetic interference allows the system to be used by multiple vehicles as a team.[23] The 27-volt system requires approximately one kilowatt of power, and weighs around 1,100 kilograms (2,400 lb).[11] Arena increases a tank's probability of surviving a rocket-propelled grenade by between 1.5[11]–2 times.[24]

Despite being very interesting, It seems this system is not in use but is available for export versions

Last gen deployed on Armata vehicles:

Afganit (Russian: Афганит, lit. 'Afghanite') is a Russian active protection system (APS) employed on modern Russian Armata family of vehicles.[1] It is intended to supersede the Arena APS and utilises radar and electro-optical sensors in the ultraviolet and infrared bands.[2][3] The millimeter-wavelength radar detects and tracks incoming anti-tank munitions. The system can reportedly intercept armour-piercing fin-stabilized discarding sabot kinetic energy penetrators in addition to high-explosive anti-tank (HEAT) munitions.[4][5] Currently, the maximum speed that can be intercepted is 1,700 m/s (Mach 5.0), with projected future increases of up to 3,000 m/s (Mach 8.8).[6] According to news sources, it protects the tank from all sides.[7][8]

A few armata (not the T-14) have been seen in Ukraine but not meaningfully deployed yet.

Interestingly Ukraine has its own APS:

https://en.wikipedia.org/wiki/Zaslin_Active_Protection_System however I have no clue how much it is used in practice?

About the US prototype APS:

n 2006–2007, the Institute for Defense Analysis found Quick Kill to be relatively immature and had significant development risks. Important components such as the radar were not yet fully developed and testing of the system as a whole was on hold while the warhead was redesigned. They also found Trophy, which uses a shotgun-like kill mechanism, to be the most mature of the 15 systems they analyzed.

while the other one seems promising:

However, in August 2018 the Army decided not to continue qualifying Iron Curtain onto the Stryker, saying that while the system "generally worked in concept" and was "generally able to hit its targets," it was still not mature enough.[11]

China recently deployed the GL-5 which has a range of 100 meters, twice that of arena (no clue for afganit)

https://en.wikipedia.org/wiki/GL5_Active_Protection_System

innovative since it launch 2 rockets.

The irsaely trophy seems interesting. Gun based.

almost completely negate legacy ATGMs unless paired with a sophisticated jamming attack ..

This is an unrealistic claim as of yet.

Firstly as we can see, at least for Russia and the U.S, hard kill APS are nothing more than uncertain and possibly buggy proof of concepts.

Russia did deploy some successfully in afghanistan but the fact they didn't deploy them shows that the tech is mostly not ready.

It could be that the new APS system on armatas is disruptives and working well, but that is unproven. It's possible but uncertain that using recent machine learning techniques would yield lower danger/false positives but given the classical inertia, if that were the answer, we're not ready to see that deployed until 20 years, and even so ML techniques have generally dangerous error rates.

It would be interesting to evaluate how much deployed in the wild are the ukrainian and chinese and israeli APS systems are though.

and what about hard kill APS for aircrafts/helicos?

As for soft kill APS, well russia is the only to have one widely deployed but Ukraine still manage to destroy T-90s just fine.

beyond the real world production ready-ness/falsepositives issues/safety of hard kill APS, what the manufacturer says is not necessarily objective truth

about the range, the claimed 360 degree coverage, reaction time, etc

especially I suspect many APS are weak and possibly useless against top-down attacking ATGMS: https://en.wikipedia.org/wiki/Active_protection_system#Top_attack_munitions

Overall I am very curious about the future of this technology and we might get answers either by:

studying academic papers/experiments about them

waiting for a china-taiwan war (unlikely)

waiting for a new israel based war (no idea)

waiting for the ukrainian APS system to be deployed or for western countries giving APS to ukraine (e.g. germany supposedly has one)

waiting for the armata systems to see some action in Ukraine, most likely but only if the war last a few years.

But your initial point is wrong, ATGMs have currently and probably for the foreasable future, destroyed tanks economics.

Ukraine as a country isn't particularly important

It depends what you mean by that, indeed a russian takeover wouldn't directly change the world but Ukraine and Russia are the largest food exporters in the world IIRC.

Ukraine also has (had?) a monopoly in noble gas.

Ukraine was a key driver of Soviet science, engineering and military tech, see e.g the antonov which would BTW enable cheaply to have a potent successor to Hubble if anyone cared as usual.

However Ukraine has lost all its technological glory since the population will to stay in the USSR has not been respected https://en.wikipedia.org/wiki/1991_Soviet_Union_referendum

I have extensively studied almost all nootropics and therefore know most of the pharmacological markers that influence intelligence, however I have almost zero knowledge about the genetics correlate of hypermnesy, intelligence and rationality.

Does anyone know what are key "genius" genes?

IMHO I don't think intelligence is mostly bottlenecked by standard genetics, I am far more inclined to believe in early nurturial critical periods.

But I do believe in the potential of a practice that has long been forgotten, artificial cranial elongation:

https://en.wikipedia.org/wiki/Artificial_cranial_deformation#/media/File:Afrasiab,_elongated_skull_600-800_CE,_Afrasiab_Museum.jpg

According to scientists their brain volume is not bigger than a normal human being, and as such cranial elongation only solves one bottleneck: space.

If we identify the mechanics that drive the closing of the brain surface in teenage years and find a way to delay it, or if we intensify neuron and axonal growth during childhood via e.g. BDNF, NGF, etc and maybe growth hormone then we might achieve humans with the biggest brains ever.

Don't get me wrong brain size is only one metric and there might be a bimodal curve to it however our current brain size as shown by studies is totally constrained by a mere contingent scarce sugar consumption optimisation.

Has any mottizen seen the masterpiece that is Don't Hug Me I'm Scared? If so what did you feel about it? What did you think about it? And what content would you recommend based on this taste?

Unrelated but his book the art of being right is a great one for learning logical fallacies.

I feel like this idea has become quite popular since the egg video of in a nutshell.

The unification of qualia experiences by having no physical delineation is the most epistemologically sound metaphysical belief since it avoid many paradoxes.

What is the formal name of this belief and who postulated it first?

I haven't studied the gerontology of spermatogenesis but IIRC you loose ~16% of your testosterone secretion per decade.

Something similar must apply to your

luteinizing hormone I guess.

It's likely antioxidants reduce spermatogenesis loss, I believe I had read studies about that a long time ago.

Spermatogenesis should mostly be a solved problem, IIRC Ashwaganda +100%> ?

HCG, etc

But indeed the real problem is the dna degradation of your sperm.

There was a paper on hackernews this week, about increased epigenetic heritage loss for aged males.

Despite my erudition in gerontology I have never been able to find a compelling answer as to why life on earth works.

As we live we accumulate mutations, 60000 per day. Yes our sperm is much more protected than the rest but even if sperm age slower than the rest, it still age. And therefore that Ageing should be passed and herited to the offspring.

Therefore by generation to generation we should dramatically accumulate buggy mutations.

And yet, mysteriously, we don't.

How is this possible and how isn't this technology the way to achieve cellular and therefore eventually possibly whole body Immortality?

Oversized glasses are one of the many artificial nudge/enhancers one can use.

It is an instance of a supra-normal stimulus

https://www.edge.org/response-detail/27203

https://m.fr.aliexpress.com/item/32812104344.html?gatewayAdapt=gloPc2fraMsite

I'm intrigued by your gender neutral comment though. Would you see those oversized glasses on a man face?

Close to zero straight men assume that looks currently.

IMO I think it could enhance a man's look although as usual people have a completely broken idea of what a maximally attractive man looks like.

The strangest thing you've found yourself attracted to in someone else?

I should definitely come back to that question, I am in complete awe with many things that some people do that are quite ineffable yet charming.

Humans are so awkward, imperfect and so fucking lovely.

The best compliment I've received lately was that some of my comments were so semantically dense it were intensely charming. As a semi-sapiosexual that's indeed one of my compliments lifegoal :)

Once someone was immensely impressed by the fact that I carried a phone without a case.

Relatable, at first I was really stressing about it but actually it's quite trivial to not let ur phone fall.

I recall reading that people with exceptionally good memories have a hard time connecting with people because they remember in vivid detail every slight that was ever done to them. And that being somewhat forgetful is a necessary component for forgiveness. Sociolopsychology is fickle.

I can relate to that for another reason. I see people each year having the same conversations they already had years ago and they repeat the script as if it was for the first time.

I mean sure, it's great to bypass the hedonic treadmill and to be excited about things you already talked about in the past.

Me remembering things indeed maintain a bit my hedonic treadmill but the worst by far is to see the non-evolution, instead of taking the occasion of the discussion to explore the semantic search space differently, more in breadth and or more in depth, it is tiring to see the striking human stagnation.

women rate him less attractive than men

Interesting, sauce?

Excellent comment, very much appreciated.

It's not everyday someones manage to teach me a new concept :)

Quite a crazy coincidence, I saw this word before your comment yesterday by pure luck https://semanticsarchive.net/Archive/WNjOWZiY/

It often happen to me, to see something apparently (?) for the first time in my life and then to see it again, in the following days out of pure coincidence.

While I'm tempted to believe such coincidence have a mystic nature, the insight I derive from this phenomenon is that I must have a cognitive bias of being blind to unknown words, that is until I see a proper definition of them. Kinda sad.

Anyway back on the topic, would there be a way to use an obviative pronoun in english without sounding too robotic/unnatural?

An ambiguous "is maybe an object" is preferable to "is maybe plural" since contextual confusion about the former is extremely less likely than the later.

But yeah ideally we would create a new gender neutral singular pronoun.

[Neural networks] are a local minima in the research on how to beat local minimas.

Could you expand what you mean by this? I'd think neural networks would be a local maximum.

Minimum, maximum, it doesn't matter to understand the metaphor.

A neural network through gradient descent generally want to find the global minimum of an error function and therefore maximize predictions accuracy.

It could instead search for a global maximum to the inverse of an error function or to another type of function, but the distinction is irrelevant here.

Gradient descent often fail to find the global minimum and instead because it descent/jump through derivates it can be stuck in a local minima, which simply means that it has reached a minima on a function curve and at this point, it needs to go upwards to go beyond the minima, therefore it temporarily afford to perform worse, to increase the error rate, in hope to find a new descent on the curve that will be lower than the previous minima

Not being stuck in local minima is the #1 metric to improve deep learning algorithms and while there are many optimizations towards this goal it is not computationally doable with current algorithms to have optimal learning aka reach the global minima.

So now we understand

the research on how to beat local minimas == neural networks.

now let's understand

[Neural networks] are a local minima

They are a local minima because Neural networks are fundamentally unfit towards AGI needs.

They are just a vomit of bruteforced contingent correlates and it works surprisingly well but it is inefficient, makes poor contingent amalgamations inherently,

have no causal reasoning abilities, are stateless and cannot do continual learning AKA they can't learn new info in real time without the so called catastrophic forgetting.

For those reasons, they are by design suboptimals and therefore are a local minima in which the world is stuck, in the goal of beating local minimas.

Now we are in another period of rapid advancement.

No offence, but it's really striking to see that the rationalist diaspora people live in an alternate reality based on groundless hype and a fundamental lack of methodology, or should I dare say, lack of rationality.

We are in a winter since 2019 or since the 90s depending on what we look at.

What does the average lesswronger or redditor look at?

He looks at cool demos. Or even more than demos, cool domain specific disrutpive applications.

That is what stablediffusion and chatgpt are.

They are indeed very impressive for what they do but at the end of the day that is irrelevant towards the natural language understanding goal.

someome with methodology should instead look at the precise tasks required towards true NLU or even AGI.

POS tagging:

https://paperswithcode.com/sota/part-of-speech-tagging-on-penn-treebank

dependency parsing:

https://paperswithcode.com/sota/dependency-parsing-on-penn-treebank

coreference resolution

https://paperswithcode.com/sota/coreference-resolution-on-ontonotes

word sense disambiguation

https://paperswithcode.com/sota/word-sense-disambiguation-on-supervised

named entity recognition

https://paperswithcode.com/sota/named-entity-recognition-ner-on-conll-2003

semantic parsing

https://paperswithcode.com/sota/semantic-parsing-on-amr-english-mrp-2020

Only to name a few, all of them are needed concomitantly, and that is by far non-exhaustive.

Once you undestand that the error rate is often per word/token instead of per sentence, and that error between those tasks have dependencies and are therefore often multiplicative and you'll undestand that a 95% accuracy while it sounds impressive is in fact dogshit.

What can you see from those SOTA results?

That we have reached a plateau of extreme and increasingly diminishing returns.

Most of the gains are from 2019, the year transformers were popularized. The rest has been a bag of tricks, and unoriginal minor optimizations.

The biggest innovation while still mostly unknown/underappreciated by the researchers group think, is XLnet, from 2019 too.

There is nothing else we can do, we have maxxed out the bruteforcing of statistics amalgamations, contrary to the belief, there is almost zero progress in SOTA results and most importantly there is a fundamental shortage of innovative ideas, wether we speak of an alternative to transformers or about innovating transformers themselves, nothing potent.

While it is obvious transformers are a misdirection, despite this I can improve the state of the art in any NLP task because there are additional ineptia in the research crowd.

Firstly almost nobody is working on improving the SOTA in most tasks, e.g. coreference resolution. Just look at the number of submisions over time to realize this.

Secondly as in every research field, the researchers are highly dysfunctional, AKA they will invent many minor but interesting, universal and complementary/synergetic optimizations ideas and yet nobody will ever attempt to combine them concomitantly, despite it being trivial. That is because researchers are not meta-researchers, and because of potent NIH syndrome and other cognitive biases.

For starters, the worldwide SOTA in dependency parsing is because I asked the researcher to switch BERT for XLnet, and it worked.

I plan to outperform the SOTA in coreference resolution in 2023, that will empirically strengthen my thesis on the dysfunctionality of mankind and on artificial scarcity.

I invite you to read this complementary essay on the topic: https://www.metaculus.com/notebooks/10677/substance-is-all-you-need/

VoiceOfLogic

You can issue corrections, prompt it with more information, tell it to adjust something, and it'll do it.

How is this implemented? Neural networks are universally stateless.

What recently gave you emotional tears? (sublimation)

Tendons.. nobody knows shit about how to fix them

Well the thing is simply that doctors are scientifically illiterate, unlike me. The most potent drug at repairing tendons is BPC-157 which is a peptide endogenously produced in the body. It is available OTC for a short term injections cycle, the most reputable website but a bit pricey is peptidesciences .com https://pubmed.ncbi.nlm.nih.gov/14554208/ BPC is quite popular on /r/peptides and has "saved" many, however it is a serious medication that shouldn't be taken without studying its tradeoffs (short term anhedonia risk, amphetamine blunting and increased angiogenesis (therefore increased lifespan if young, increased risk of metastasis if old)

As usual men are doomed as they are in large amounts, simps or to some extent, endoctrinated self-hating misandrists. Note however that biologically speaking there are reasons for the shorter lifespan of men though, the biggest one probably being height. height is one of the strongest predictor of low life expectancy. Basically anabolism has costs, including some immuno deficits in terms of resource allocation, possibly increased oxdative stress and cancer risk. It might be that short and non-high bmi men live longer than the average woman though? But mens body also has advantages, for example increased brain volume means men are less prone to neurodegenerative diseases, especially for example, 2 times less chance of developing multiple sclerosis (although the specific reason here being that testosterone increase myelin production)

Now as a reminder, you can increase significantly your lifespan via skq1.

However the biggest omission in your blog, and the question that leaves me most curious, is a comparison of women/men not lifespan but healthspan I already talked about dementia but what about sarcopenia (should advantage men too) and what about chronic hospitalizations rate per age? I suppose the gap of ill men (especially cancer) is even bigger than the gap of prematurely dead men.

Also a question no ones asked before, are baby boys more often victims of baby shaken syndrome by their parents?

This is very well written